Congenital rubella syndrome overview: Difference between revisions
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[[Congenital rubella syndrome]] is caused by [[rubella]] virus which is a single stranded [[RNA]] toga virus. | [[Congenital rubella syndrome]] is caused by [[rubella]] virus which is a single stranded [[RNA]] toga virus. | ||
==Differentiating Congenital Rubella Syndrome from other Diseases== | ==Differentiating Congenital Rubella Syndrome from other Diseases== | ||
[[Congenital rubella syndrome]] has to be differentiated from other congenital infections ([[TORCH|TORCH infections]]) as they may have some overlapping features. | [[Congenital rubella syndrome]] has to be differentiated from other congenital infections ([[TORCH complex|TORCH infections]]) as they may have some overlapping features. | ||
== Epidemiology and Demographics == | == Epidemiology and Demographics == | ||
Revision as of 18:56, 19 December 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: :Kalsang Dolma, M.B.B.S.[2]
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Overview
Congenital rubella syndrome (CRS) can occur in a developing fetus of a pregnant woman who has contracted rubella during her first trimester. Problems rarely occur when rubella is contracted by the mother after 20 weeks of gestation.
Pathophysiology
Congenital rubella syndrome results from the spread of infection to fetus by mother during viremic stage. Rubella virus enters fetus through the placenta and cause damage to all germ layers of fetus. This results in rapid death of some cells.
Causes
Congenital rubella syndrome is caused by rubella virus which is a single stranded RNA toga virus.
Differentiating Congenital Rubella Syndrome from other Diseases
Congenital rubella syndrome has to be differentiated from other congenital infections (TORCH infections) as they may have some overlapping features.
Epidemiology and Demographics
Congenital rubella syndrome is rare in developed countries with strong immunization programs. It is endemic in other parts of the world.
Treatment
Medical Therapy
There is no specific treatment for congenital rubella syndrome. Symptoms are treated as appropriate. Management for ocular congenital rubella syndrome (CRS) is similar to that for age-related macular degeneration, including counseling, regular monitoring, and the provision of low vision devices, if required.[1]
Surgery
Treatment of newly born babies is focused on management of the complications. Congenital heart defects and cataracts can be corrected by direct surgery.[2]
References
- ↑ Weisinger HS, Pesudovs K (2002). "Optical complications in congenital rubella syndrome". Optometry. 73 (7): 418–24. PMID 12365660.
- ↑ Khandekar R, Sudhan A, Jain BK, Shrivastav K, Sachan R (2007). "Pediatric cataract and surgery outcomes in Central India: a hospital based study". Indian J Med Sci. 61 (1): 15–22. doi:10.4103/0019-5359.29593. PMID 17197734.