Complications Based Questions

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Frequently Asked Inpatient Questions Microchapter

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]: Associate Editor(s)-in-Chief:

Complications Based Questions

What population is most at risk for severe disease from COVID-19?

  • COVID-19 is a new disease and there is limited information regarding risk factors for severe illness. Based on currently available information and clinical expertise, older adults and people of any age who have serious underlying medical conditions might be at higher risk for severe illness from COVID-19.[1]

What risk factors result in severe complications from COVID-19?

  • Information on COVID-19 evolves daily. Current known risk factors include but are not limited to underlying chronic conditions such as; lung disease, moderate to severe asthma, cardiac disease with complications, diabetes, or immunocompromising conditions.[2]

What systems other than the Respiratory system can be involved?

  • Although research for COVID-19 I still ongoing, scientists have found extrapulmonary manifestations in several other systems. It is thought that the virus instigates a "cytokine storm" where the body responds massively, leading to widespread cytokine release, cellular, tissue, and organ damage. Extrapulmonary manifestations include but are not limited to;[3]
    • Heart Inflammation
    • Neurologic manifestations
    • Renal disease
    • Liver and digestive tract compromise
    • Venous thromboembolism.

Does prolonged ventilation in hospitalized patients worsen the outcome of COVID-19?

Sources

  1. "People Who Are at Higher Risk for Severe Illness | Coronavirus | COVID-19 | CDC".
  2. "Clinical Questions about COVID-19: Questions and Answers | CDC".
  3. "COVID-19: Damage found in multiple organ systems | MDLinx".