Colorectal cancer laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
The laboratory findings associated with colorectal carcinoma are the following: CBC, FOBT, serum CEA and CA 19-9 concentration, serum iron concentrations, serum vitamin B12 and folate concentrations, liver function tests, and pulmonary function tests. | The laboratory findings associated with colorectal carcinoma are the following: [[Complete blood count|CBC]], [[FOBT]], [[CEA|serum CEA]] and [[CA 19-9|CA 19-9 concentration]], [[Serum iron|serum iron concentrations]], [[Vitamin B12|serum vitamin B12]] and [[Folate|folate concentrations]], [[liver function tests]], and [[pulmonary function tests]]. | ||
== Colorectal Cancer Laboratory Findings== | == Colorectal Cancer Laboratory Findings== | ||
*Complete blood count and differential count - [[anemia]] | *[[Complete blood count]] and differential count - [[anemia]] | ||
*[[Fecal occult blood test]]([[FOBT]]) - demonstrates occult bleeding from the intestines | *[[Fecal occult blood test]]([[FOBT]]) - demonstrates occult bleeding from the intestines | ||
*Serum [[carcino-embryogenic antigen]] ([[CEA]]) and CA 19-9 - elevated concentrations are associated with large tumor masses, and have a poor prognosis | *Serum [[carcino-embryogenic antigen]] ([[CEA]]) and [[CA 19-9]] - elevated concentrations are associated with large tumor masses, and have a poor prognosis | ||
*Low serum iron levels | *Low serum iron levels | ||
:*Individuals with microcytic anemia over 50 years of age are suspected of having colorectal cancer<ref name="ZhuKaneshiro2010">{{cite journal|last1=Zhu|first1=Amy|last2=Kaneshiro|first2=Marc|last3=Kaunitz|first3=Jonathan D.|title=Evaluation and Treatment of Iron Deficiency Anemia: A Gastroenterological Perspective|journal=Digestive Diseases and Sciences|volume=55|issue=3|year=2010|pages=548–559|issn=0163-2116|doi=10.1007/s10620-009-1108-6}}</ref> | :*Individuals with [[microcytic anemia]] over 50 years of age are suspected of having colorectal cancer<ref name="ZhuKaneshiro2010">{{cite journal|last1=Zhu|first1=Amy|last2=Kaneshiro|first2=Marc|last3=Kaunitz|first3=Jonathan D.|title=Evaluation and Treatment of Iron Deficiency Anemia: A Gastroenterological Perspective|journal=Digestive Diseases and Sciences|volume=55|issue=3|year=2010|pages=548–559|issn=0163-2116|doi=10.1007/s10620-009-1108-6}}</ref> | ||
*Low serum vitamin B12 and folate levels | *Low serum [[vitamin B12]] and [[folate]] levels | ||
*Hypercalcemia - with metastasis to the bone | *[[Hypercalcemia]] - with metastasis to the bone | ||
===Test for Metastasis=== | ===Test for Metastasis=== | ||
Revision as of 14:01, 18 December 2017
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To view the laboratory findings of familial adenomatous polyposis (FAP), click here
To view the laboratory findings of hereditary nonpolyposis colorectal cancer (HNPCC), click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.
Overview
The laboratory findings associated with colorectal carcinoma are the following: CBC, FOBT, serum CEA and CA 19-9 concentration, serum iron concentrations, serum vitamin B12 and folate concentrations, liver function tests, and pulmonary function tests.
Colorectal Cancer Laboratory Findings
- Complete blood count and differential count - anemia
- Fecal occult blood test(FOBT) - demonstrates occult bleeding from the intestines
- Serum carcino-embryogenic antigen (CEA) and CA 19-9 - elevated concentrations are associated with large tumor masses, and have a poor prognosis
- Low serum iron levels
- Individuals with microcytic anemia over 50 years of age are suspected of having colorectal cancer[1]
- Low serum vitamin B12 and folate levels
- Hypercalcemia - with metastasis to the bone
Test for Metastasis
- Abnormal liver function tests
- Abnormal pulmonary function tests
References
- ↑ Zhu, Amy; Kaneshiro, Marc; Kaunitz, Jonathan D. (2010). "Evaluation and Treatment of Iron Deficiency Anemia: A Gastroenterological Perspective". Digestive Diseases and Sciences. 55 (3): 548–559. doi:10.1007/s10620-009-1108-6. ISSN 0163-2116.