Colorectal cancer history and symptoms

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To view the history and symptoms of familial adenomatous polyposis (FAP), click here
To view the history and symptoms of hereditary nonpolyposis colorectal cancer (HNPCC), click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.; Elliot B. Tapper, M.D. Usama Talib, BSc, MD [2]

Overview

The history of a patient with colorectal cancer may include a family history of polyps/colorectal cancer or a history of inflammatory bowel disease. Some symptoms that are associated with colorectal cancer are change in bowel habits, hematochezia, and rectal pain. Metastatic symptoms include dyspnea, abdominal pain, fractures, and confusion.

Colorectal Cancer History and Symptoms

Colon cancer often causes no symptoms until it has reached a relatively advanced stage. When symptoms do occur, they depend on the site of the lesion. Generally speaking, the nearer the lesion is to the anus, the more bowel symptoms there will be, such as:[1][2][3]

  • Change in bowel habits
  • Change in frequency (constipation and/or diarrhea)
  • Change in the quality of stools
  • Change in consistency of stools
  • Hematochezia or bleeding per rectum
  • Mucus in stools
  • Abdominal cramps or discomfort
  • Melena (usually associated with upper gastrointestinal disease)
  • Tenesmus (usually associated with rectal cancer)
  • Diminished caliber of stools (usually associated with rectal cancer)
  • Rectal pain (usually associated with rectal cancer)
  • Past medical history of longstanding inflammatory bowel disease, diabetes, another primary cancer, or renal transplantation
  • Family history of polyps or colorectal cancer
  • Smoking and/or alcohol
  • Low fiber/high fat diet and/or red meat diet
  • Sedentary lifestyle

Constitutional symptoms

The constitutional symptoms of colorectal carcinoma include:[4]

Metastatic symptoms

There may be symptoms attributed to distant metastasis:[5][6][7]

  • Lungs
    • Dyspnea
    • Cough with blood-stained sputum
    • Persistent pain or discomfort in the chest
  • Liver
  • Bones
  • Brain/spinal cord
  • Oral Cavity
    • Gum pain
    • Inability to open the mouth

References

  1. Carmen Jochem & Michael Leitzmann (2016). "Obesity and Colorectal Cancer". Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 208: 17–41. doi:10.1007/978-3-319-42542-9_2. PMID 27909900.
  2. Hind Mrabti, Mounia Amziren, Ibrahim ElGhissassi, Youssef Bensouda, Narjiss Berrada, Halima Abahssain, Saber Boutayeb, Samira El Fakir, Chakib Nejjari, Abdellatif Benider, Nawfel Mellas, Omar El Mesbahi, Maria Bennani, Rachid Bekkali, Ahmed Zidouh & Hassan Errihani (2016). "Quality of life of early stage colorectal cancer patients in Morocco". BMC gastroenterology. 16 (1): 131. doi:10.1186/s12876-016-0538-9. PMID 27733117. Unknown parameter |month= ignored (help)
  3. Yasmine Samir Galal, Tarek Tawfik Amin, Abdulelah Khalid Alarfaj, Abdulaziz Abdullah Almulhim, Abdullah Abdulmohsen Aljughaiman, Abdulrhaman Khaled Almulla & Rehab Ahmed Abdelhai (2016). "Colon Cancer among Older Saudis: Awareness of Risk Factors and Early Signs, and Perceived Barriers to Screening". Asian Pacific journal of cancer prevention : APJCP. 17 (4): 1837–1846. PMID 27221862.
  4. Yasmine Samir Galal, Tarek Tawfik Amin, Abdulelah Khalid Alarfaj, Abdulaziz Abdullah Almulhim, Abdullah Abdulmohsen Aljughaiman, Abdulrhaman Khaled Almulla & Rehab Ahmed Abdelhai (2016). "Colon Cancer among Older Saudis: Awareness of Risk Factors and Early Signs, and Perceived Barriers to Screening". Asian Pacific journal of cancer prevention : APJCP. 17 (4): 1837–1846. PMID 27221862.
  5. Samir Pathak, Sanjay Pandanaboyana, Ian Daniels, Neil Smart & K. R. Prasad (2016). "Obesity and colorectal liver metastases: Mechanisms and management". Surgical oncology. 25 (3): 246–251. doi:10.1016/j.suronc.2016.05.021. PMID 27566030. Unknown parameter |month= ignored (help)
  6. Masato Watanabe, Masanori Tada, Takafumi Satomi, Daichi Chikazu, Masashi Mizumoto & Hideyuki Sakurai (2016). "Metastatic rectal adenocarcinoma in the mandibular gingiva: a case report". World journal of surgical oncology. 14 (1): 199. doi:10.1186/s12957-016-0958-6. PMID 27473859. Unknown parameter |month= ignored (help)
  7. Vivek Subbiah & Howard Jack West (2016). "Jaundice (Hyperbilirubinemia) in Cancer". JAMA oncology. 2 (8): 1103. doi:10.1001/jamaoncol.2016.1236. PMID 27416009. Unknown parameter |month= ignored (help)


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