Colorectal cancer epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
Colorectal cancer is the third most commonly diagnosed cancer in the world, and accounts for 8% of all cancer-related deaths annually | Colorectal cancer is the third most commonly diagnosed [[cancer]] in the world, and accounts for 8% of all cancer-related deaths annually. In the United States, the [[prevalence]] of colorectal cancer is 376.3 per 100,000 persons, and the [[incidence]] is 42.9 per 100,000 persons. The [[incidence]] of colorectal cancer is higher in males, the elderly, and in the African American race. | ||
==Epidemiology and | ==Epidemiology and Demographics== | ||
The epidemiology and demographics of colorectal carcinoma can be explained as follows: | The [[epidemiology]] and [[demographics]] of colorectal carcinoma can be explained as follows: | ||
===Prevalence=== | ===Prevalence=== | ||
*In 2012, the prevalence of colorectal cancer was 376.3 per 100,000 persons in the United States<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | *In 2012, the [[prevalence]] of colorectal cancer was 376.3 per 100,000 persons in the United States<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | ||
===Incidence=== | ===Incidence=== | ||
*From 2001-2010, the overall incidence rates of colorectal cancer has decreased by an average of 3.4% per year<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | *From 2001-2010, the overall [[incidence]] rates of colorectal cancer has decreased by an average of 3.4% per year<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | ||
*In 2014, the incidence of colorectal cancer was 42.9 per 100,000 persons in the United States<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | *In 2014, the [[incidence]] of colorectal cancer was 42.9 per 100,000 persons in the United States<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | ||
*In 2014, the incidence of colorectal deaths was 5.8 per 100,000 persons in the United States | *In 2014, the [[incidence]] of colorectal deaths was 5.8 per 100,000 persons in the United States | ||
===Age=== | ===Age=== | ||
*The prevalence of colorectal cancer increases with age<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | *The [[prevalence]] of colorectal cancer increases with age<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | ||
*The percentage of 50 year old men that may develop colorectal cancer in 10, 20, and 30 years, respectively, is 0.68, 1.84, and 3.39<ref>http://seer.cancer.gov/csr/1975_2011/browse_csr.php?sectionSEL=6&pageSEL=sect_06_table.19.html</ref> | *The percentage of 50 year old men that may develop colorectal cancer in 10, 20, and 30 years, respectively, is 0.68, 1.84, and 3.39<ref>http://seer.cancer.gov/csr/1975_2011/browse_csr.php?sectionSEL=6&pageSEL=sect_06_table.19.html</ref> | ||
*The percentage of 50 year old women that may develop colorectal cancer in 10, 20, and 30 years, respectively, is 0.52, 1.37, and 2.69<ref>http://seer.cancer.gov/csr/1975_2011/browse_csr.php?sectionSEL=6&pageSEL=sect_06_table.20.html</ref> | *The percentage of 50 year old women that may develop colorectal cancer in 10, 20, and 30 years, respectively, is 0.52, 1.37, and 2.69<ref>http://seer.cancer.gov/csr/1975_2011/browse_csr.php?sectionSEL=6&pageSEL=sect_06_table.20.html</ref> | ||
===Gender=== | ===Gender=== | ||
*Worldwide, colorectal cancer is the third most commonly diagnosed cancer when men and women are considered separately, and the second leading cause when both sexes are combined | *Worldwide, colorectal cancer is the third most commonly diagnosed [[cancer]] when men and women are considered separately, and the second leading cause when both sexes are combined | ||
*The incidence and mortality rates are 20% to 40% higher in men than in women<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | *The [[incidence]] and [[mortality]] rates are 20% to 40% higher in men than in women<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref> | ||
*The male to female incidence rate ratio (IRR) is<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>: | *The male to female [[incidence]] rate ratio (IRR) is<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>: | ||
:*1 to 1 - birth to 49 years | :*1 to 1 - birth to 49 years | ||
:*1 to 4 - 50 to 79 years | :*1 to 4 - 50 to 79 years | ||
Revision as of 15:56, 15 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.
Overview
Colorectal cancer is the third most commonly diagnosed cancer in the world, and accounts for 8% of all cancer-related deaths annually. In the United States, the prevalence of colorectal cancer is 376.3 per 100,000 persons, and the incidence is 42.9 per 100,000 persons. The incidence of colorectal cancer is higher in males, the elderly, and in the African American race.
Epidemiology and Demographics
The epidemiology and demographics of colorectal carcinoma can be explained as follows:
Prevalence
- In 2012, the prevalence of colorectal cancer was 376.3 per 100,000 persons in the United States[1]
Incidence
- From 2001-2010, the overall incidence rates of colorectal cancer has decreased by an average of 3.4% per year[1]
- In 2014, the incidence of colorectal cancer was 42.9 per 100,000 persons in the United States[1]
- In 2014, the incidence of colorectal deaths was 5.8 per 100,000 persons in the United States
Age
- The prevalence of colorectal cancer increases with age[1]
- The percentage of 50 year old men that may develop colorectal cancer in 10, 20, and 30 years, respectively, is 0.68, 1.84, and 3.39[2]
- The percentage of 50 year old women that may develop colorectal cancer in 10, 20, and 30 years, respectively, is 0.52, 1.37, and 2.69[3]
Gender
- Worldwide, colorectal cancer is the third most commonly diagnosed cancer when men and women are considered separately, and the second leading cause when both sexes are combined
- The incidence and mortality rates are 20% to 40% higher in men than in women[1]
- The male to female incidence rate ratio (IRR) is[1]:
- 1 to 1 - birth to 49 years
- 1 to 4 - 50 to 79 years
- 1 to 2 - 80 years and older
Race
- The African American race has the highest rate of colorectal cancer, and the Asian Pacific Islander race has the lowest rate of colorectal cancer[1]
- In 2006-2010, the colorectal cancer incidence rates among the African American race were approximately 25% higher than the Caucasian race and 50% higher than the Asian Pacific Islander race[1]
- In 2006-2010, colorectal cancer mortality rates were the following[1]:
- 29.4 per 100,000 African Americans
- 19.2 per 100,000 Caucasians
- 13.1 per 100,000 Asian Pacific Islanders
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Siegel, Rebecca; DeSantis, Carol; Jemal, Ahmedin (2014). "Colorectal cancer statistics, 2014". CA: A Cancer Journal for Clinicians. 64 (2): 104–117. doi:10.3322/caac.21220. ISSN 0007-9235.
- ↑ http://seer.cancer.gov/csr/1975_2011/browse_csr.php?sectionSEL=6&pageSEL=sect_06_table.19.html
- ↑ http://seer.cancer.gov/csr/1975_2011/browse_csr.php?sectionSEL=6&pageSEL=sect_06_table.20.html