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To view the epidemiology and demographics of familial adenomatous polyposis (FAP), click [[Familial adenomatous polyposis epidemiology and demographics|'''here''']]<br>
To view the epidemiology and demographics of familial adenomatous polyposis (FAP), click [[Familial adenomatous polyposis epidemiology and demographics|'''here''']]<br>
To view the epidemiology and demographics of hereditary nonpolyposis colorectal cancer (HNPCC), click [[Hereditary nonpolyposis colorectal cancer epidemiology and demographics|'''here''']]<br><br>
To view the epidemiology and demographics of hereditary nonpolyposis colorectal cancer (HNPCC), click [[Hereditary nonpolyposis colorectal cancer epidemiology and demographics|'''here''']]<br><br>
{{CMG}} {{AE}} Saarah T. Alkhairy, M.D.
{{CMG}} {{AE}}; {{RAK}}, Saarah T. Alkhairy, M.D.


==Overview==
==Overview==
*Colorectal cancer is one of the top three most commonly diagnosed cancers in the world, and accounts for 8% of all cancer-related deaths annually<ref name="pmid24876728">{{cite journal|author=Bishehsari F, Mahdavinia M, Vacca M, Malekzadeh R, Mariani-Costantini R| title=Epidemiological transition of colorectal cancer in developing countries: environmental factors, molecular pathways, and opportunities for prevention. | journal=World J Gastroenterol | year= 2014 | volume= 20 | issue= 20 | pages= 6055-72 | pmid=24876728 |doi=10.3748/wjg.v20.i20.6055 | pmc=PMC4033445 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24876728  }}</ref>. In the United States, the prevalence of colorectal cancer is 376.3 per 100,000 persons, and the incidence is 42.9 per 100,000 persons. The incidence of colorectal cancer is higher in males, the elderly, and in the African American race.
Colorectal cancer is the third most commonly diagnosed [[cancer]] in the world, and accounts for 8% of all cancer-related deaths annually. In the United States, the [[prevalence]] of colorectal cancer is 376.3 per 100,000 persons, and the [[incidence]] is 42.9 per 100,000 persons. The [[incidence]] of colorectal cancer is higher in males, the elderly, and in the African American race.


==Prevalence==
==Epidemiology and Demographics==
*In 2012, the prevalence of colorectal cancer was 376.3 per 100,000 persons in the United States<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
The [[epidemiology]] and [[demographics]] of colorectal carcinoma can be explained as follows:
===Incidence===
*In 2014, the [[incidence]] of colorectal cancer was estimated to be 42.9 cases per 100,000 persons in the United States<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*From 2001-2010, the overall [[incidence]] rates of colorectal cancer has decreased by an average of 3.4% per year<ref name="SiegelDeSantis2014" />
*In 2014, the [[incidence]] of colorectal deaths was 5.8 per 100,000 persons in the United States.<ref name="SiegelDeSantis2014" />
===Prevalence===
*In 2012, the [[prevalence]] of colorectal cancer was estimated to be 376.3 cases per 100,000 individuals in the United States<ref name="SiegelDeSantis2014" />


==Incidence==
===Age===
*From 2001-2010, the overall incidence rates of colorectal cancer has decreased by an average of 3.4% per year<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*The incidence of colorectal cancer increases with age.<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*In 2014, the incidence of colorectal cancer was 42.9 per 100,000 persons in the United States<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*In 2014, the incidence of colorectal deaths was 5.8 per 100,000 persons in the United States<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*It is predicted that the incidence of colorectal cancer will dramatically increase over the next decade from 376.3 per 100,000 persons to 690.0 per 100,000 persons worldwide, with most of the new cases occurring in developing countries (62% approximately)<ref name="pmid24876728">{{cite journal| author=Bishehsari F, Mahdavinia M, Vacca M, Malekzadeh R, Mariani-Costantini R| title=Epidemiological transition of colorectal cancer in developing countries: environmental factors, molecular pathways, and opportunities for prevention. | journal=World J Gastroenterol | year= 2014 | volume= 20 |issue= 20 | pages= 6055-72 | pmid=24876728 | doi=10.3748/wjg.v20.i20.6055 | pmc=PMC4033445 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24876728  }} </ref>


==Age==
===Race===
*The prevalence of colorectal cancer increases with age<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
* Colorectal cancer usually affects individuals of the African American race. Asian Pacific Islander individuals are less likely to develop colorectal cancer.<ref name="SiegelDeSantis2014" />
*Approximately 60% of cases and 70% of deaths occur in those aged 65 years and older<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*In 2006-2010, the colorectal cancer incidence rates among the African American race were approximately 25% higher than the Caucasian race and 50% higher than the Asian Pacific Islander race.<ref name="SiegelDeSantis2014" />
 
===Gender===
==Gender==
* Men are more commonly affected by colorectal cancer than women. The male to female ratio varies with age and is approximately:<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*Worldwide, colorectal cancer is the third most commonly diagnosed cancer in males, the second in females, and is the third cause of cancer-related mortality in both sexes
**1 to 1 - birth to 49 years
*The incidence and mortality rates are 30% to 40% higher in men than in women overall<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
**1 to 4 - 50 to 79 years
*The male to female incidence rate ratio (IRR) is<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>:
**1 to 2 - 80 years and older
:*1.1 - birth to 49 years
:*1.4 - 50 to 79 years
:*1.2 - 80 years and older
 
==Race==
*Colorectal cancer is the most prevalent among the African American race and the least prevalent among the Asian Pacific Islander race<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*In 2006-2010, the colorectal cancer incidence rates among the African American race were approximately 25% higher than the Caucasian race and 50% higher than the Asian Pacific Islander race<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*In 2006-2010, colorectal cancer mortality rates were the following<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>:
:*29.4 per 100,000 persons among African Americans
:*19.2 per 100,000 persons among Caucasians
:*13.1 per 100,000 persons among Asian Pacific Islanders 
*The incidence rate varies among certain subpulations populations, for example, the incidence of the Alaskan Native race living in Alaska is 87.1 per 100,000 persons and those living in New Mexico is 31.2 per 100,000 persons<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>
*The incidence of colorectal cancer vary widely in the United States, for example, the Caucasian race has the lowest rates in the District of Columbia and the highest rates in Kentucky<ref name="SiegelDeSantis2014">{{cite journal|last1=Siegel|first1=Rebecca|last2=DeSantis|first2=Carol|last3=Jemal|first3=Ahmedin|title=Colorectal cancer statistics, 2014|journal=CA: A Cancer Journal for Clinicians|volume=64|issue=2|year=2014|pages=104–117|issn=00079235|doi=10.3322/caac.21220}}</ref>


*Worldwide, colorectal cancer is the third most commonly diagnosed [[cancer]] when men and women are considered separately, and the second leading cause when both sexes are combined.<ref name="SiegelDeSantis2014" />
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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To view the epidemiology and demographics of familial adenomatous polyposis (FAP), click here
To view the epidemiology and demographics of hereditary nonpolyposis colorectal cancer (HNPCC), click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: ; Roukoz A. Karam, M.D.[2], Saarah T. Alkhairy, M.D.

Overview

Colorectal cancer is the third most commonly diagnosed cancer in the world, and accounts for 8% of all cancer-related deaths annually. In the United States, the prevalence of colorectal cancer is 376.3 per 100,000 persons, and the incidence is 42.9 per 100,000 persons. The incidence of colorectal cancer is higher in males, the elderly, and in the African American race.

Epidemiology and Demographics

The epidemiology and demographics of colorectal carcinoma can be explained as follows:

Incidence

  • In 2014, the incidence of colorectal cancer was estimated to be 42.9 cases per 100,000 persons in the United States[1]
  • From 2001-2010, the overall incidence rates of colorectal cancer has decreased by an average of 3.4% per year[1]
  • In 2014, the incidence of colorectal deaths was 5.8 per 100,000 persons in the United States.[1]

Prevalence

  • In 2012, the prevalence of colorectal cancer was estimated to be 376.3 cases per 100,000 individuals in the United States[1]

Age

  • The incidence of colorectal cancer increases with age.[1]

Race

  • Colorectal cancer usually affects individuals of the African American race. Asian Pacific Islander individuals are less likely to develop colorectal cancer.[1]
  • In 2006-2010, the colorectal cancer incidence rates among the African American race were approximately 25% higher than the Caucasian race and 50% higher than the Asian Pacific Islander race.[1]

Gender

  • Men are more commonly affected by colorectal cancer than women. The male to female ratio varies with age and is approximately:[1]
    • 1 to 1 - birth to 49 years
    • 1 to 4 - 50 to 79 years
    • 1 to 2 - 80 years and older
  • Worldwide, colorectal cancer is the third most commonly diagnosed cancer when men and women are considered separately, and the second leading cause when both sexes are combined.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Siegel, Rebecca; DeSantis, Carol; Jemal, Ahmedin (2014). "Colorectal cancer statistics, 2014". CA: A Cancer Journal for Clinicians. 64 (2): 104–117. doi:10.3322/caac.21220. ISSN 0007-9235.


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