Clostridium difficile infection epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
The incidence of ''C. difficile'' infection is estimated to be 20 per 100,000 person-years. In USA, the majority (65%) of cases are associated with healthcare settings, and 25% of cases are associated with previous hospitalizations. Although patients of all age groups may develop ''C. difficile'' infection, elderly patients > 65 years may have up to eight-fold increased risk of developing ''C. difficile'' infection compared with younger patients. Whites and female patients are more predisposed to develop ''C. | The incidence of ''C. difficile'' infection is estimated to be 20 per 100,000 person-years. In USA, the majority (65%) of cases are associated with healthcare settings, and 25% of cases are associated with previous hospitalizations. Although patients of all age groups may develop ''C. difficile'' infection, elderly patients > 65 years may have up to eight-fold increased risk of developing ''C. difficile'' infection compared with younger patients. Whites and female patients are more predisposed to develop ''C. difficile'' infections. Although ''C. difficile'' is abundantly reported in Europe and the United States, the infection is a global burden. | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Incidence=== | ===Incidence=== | ||
Revision as of 18:38, 21 April 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.
Overview
The incidence of C. difficile infection is estimated to be 20 per 100,000 person-years. In USA, the majority (65%) of cases are associated with healthcare settings, and 25% of cases are associated with previous hospitalizations. Although patients of all age groups may develop C. difficile infection, elderly patients > 65 years may have up to eight-fold increased risk of developing C. difficile infection compared with younger patients. Whites and female patients are more predisposed to develop C. difficile infections. Although C. difficile is abundantly reported in Europe and the United States, the infection is a global burden.
Epidemiology and Demographics
Incidence
- The incidence of C. difficile infection is estimated to be 20 per 100,000 person-years and approximately 1,500 per 100,000 hospital discharges.[1]
Age
- Patients of all age groups may develop C. difficile infection.
- Elderly patients > 65 years may have up to eight-fold increased risk of developing C. difficile infection compared with younger patients.[1]
Gender
- There is a slight female predisposition to the development of C. difficile infection with a female to male ratio of 1.26.[1]
Race
- White individuals are more predisposed to the development of C. difficile infection.[1]
Developed Countries
- The estimated number of incident C. difficile infection in USA is estimated to be approximately range between approximately 397,000 and 508,500.[1]
- In USA, the majority (65%) of cases are associated with healthcare settings, and 25% of cases are associated with previous hospitalizations.[1]
- In USA, the NAP1 C. difficile strain is more common in healthcare settings than in community settings.
- In 2011, approximately 29,000 deaths have been attributed to C. difficile infection in USA.[1]
- Several C. difficile outbreaks have been reported in Canada, USA, and Europe.
Developing Countries
- Although C. difficile is abundantly reported in Europe and the United States, the infection is a global burden.
- The burden of C. difficile in developing countries is difficult to estimate due to scarcity of available data.