Chronic pancreatitis classification: Difference between revisions
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==== Idiopathic pancreatitis: ==== | ==== Idiopathic pancreatitis: ==== | ||
*Idiopathic pancreatitis usually includes the non-alcohol induced cases of chronic pancreatitis | *Idiopathic pancreatitis usually includes the non-alcohol induced cases of chronic pancreatitis | ||
* | *Contributing factors may include: | ||
**Concealed alcohol intake | |||
**Hypersensitivity to alcohol | |||
**Unreported pancreatic trauma | |||
**Mutations in the cationic trypsinogen gene and the cystic fibrosis gene | |||
==References== | ==References== | ||
Revision as of 15:58, 3 November 2017
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Chronic pancreatitis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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American Pancreatic Association Practice Guidelines |
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Chronic pancreatitis classification On the Web |
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American Roentgen Ray Society Images of Chronic pancreatitis classification |
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Risk calculators and risk factors for Chronic pancreatitis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
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Overview
Classification
Chronic pancreatitis may be divided based on underlying morphology into:
- Large-duct type
- Small-duct type
- With calcification
- Without calcification.
Groove pancreatitis:
Groove pancreatitis is a form of segmental pancreatitis that involves confinement of the inflammation process to the groove between the duodenum, common bile duct, and head of the pancreas without any involvement of the head of pancreas.[1]
Hereditary pancreatitis:
- Hereditary pancreatitis is a subtype of chronic pancreatitis.
- It is an autosomal dominant inheritance with 80% of penetrance rate. [2]
- Symptoms usually develop <20 year of age and often <5yr age.
- It is associated with an increased risk of pancreatic adenocarcinoma.
- The management is similar to the other causes of chronic pancreatitis.
Autoimmune pancreatitis (AIP):
Tropical pancreatitis:
- It is one of the most common causes of chronic pancreatitis in tropical areas including south India.
- It was thought to be caused by cassava fruit but no longer associated with it and has no clear etiology.[3]
- It usually affects children leading to early adulthood death due to endocrine and exocrine dysfunction.
- Serine protease inhibitor SPINK1 mutations are identified in some of the patients.[4][5]
Idiopathic pancreatitis:
- Idiopathic pancreatitis usually includes the non-alcohol induced cases of chronic pancreatitis
- Contributing factors may include:
- Concealed alcohol intake
- Hypersensitivity to alcohol
- Unreported pancreatic trauma
- Mutations in the cationic trypsinogen gene and the cystic fibrosis gene
References
- ↑ Tezuka K, Makino T, Hirai I, Kimura W (2010). "Groove pancreatitis". Dig Surg. 27 (2): 149–52. doi:10.1159/000289099. PMID 20551662.
- ↑ Sossenheimer MJ, Aston CE, Preston RA, Gates LK, Ulrich CD, Martin SP, Zhang Y, Gorry MC, Ehrlich GD, Whitcomb DC (1997). "Clinical characteristics of hereditary pancreatitis in a large family, based on high-risk haplotype. The Midwest Multicenter Pancreatic Study Group (MMPSG)". Am. J. Gastroenterol. 92 (7): 1113–6. PMID 9219780.
- ↑ Sarles H, Augustine P, Laugier R, Mathew S, Dupuy P (1994). "Pancreatic lesions and modifications of pancreatic juice in tropical chronic pancreatitis (tropical calcific diabetes)". Dig. Dis. Sci. 39 (6): 1337–44. PMID 8200268.
- ↑ Bhatia E, Choudhuri G, Sikora SS, Landt O, Kage A, Becker M, Witt H (2002). "Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations". Gastroenterology. 123 (4): 1020–5. PMID 12360463.
- ↑ Schneider A, Suman A, Rossi L, Barmada MM, Beglinger C, Parvin S, Sattar S, Ali L, Khan AK, Gyr N, Whitcomb DC (2002). "SPINK1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh". Gastroenterology. 123 (4): 1026–30. PMID 12360464.