Chronic bronchitis Lung Transplant: Difference between revisions

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::1-History of hospitalization for exacerbation associated with acute hypercapnia (P co2 exceeding 50 mmHg)  
::1-History of hospitalization for exacerbation associated with acute hypercapnia (P co2 exceeding 50 mmHg)  
::2-Pulmonary hypertension or cor pulmonale, or both, despite oxygen therapy  
::2-Pulmonary hypertension or cor pulmonale, or both, despite oxygen therapy  
::3-[[FEV1]] < 20% and either [[DlCO]] < 20% or homogeneous distribution of emphysema<ref name="pmid21511083">{{cite journal |vauthors=Kreider M, Hadjiliadis D, Kotloff RM |title=Candidate selection, timing of listing, and choice of procedure for lung transplantation |journal=Clin. Chest Med. |volume=32 |issue=2 |pages=199–211 |year=2011 |pmid=21511083 |doi=10.1016/j.ccm.2011.02.001 |url=}}</ref>
::3-[[FEV1]] < 20% and either DlCO < 20% or homogeneous distribution of emphysema<ref name="pmid21511083">{{cite journal |vauthors=Kreider M, Hadjiliadis D, Kotloff RM |title=Candidate selection, timing of listing, and choice of procedure for lung transplantation |journal=Clin. Chest Med. |volume=32 |issue=2 |pages=199–211 |year=2011 |pmid=21511083 |doi=10.1016/j.ccm.2011.02.001 |url=}}</ref>
===Contraindications===
===Contraindications===
:1-Recent malignancy (other than nonmelanoma skin cancer)
:1-Recent malignancy (other than nonmelanoma skin cancer)

Revision as of 20:02, 20 September 2016

Chronic Bronchitis Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

It is primarily done for improvement of symptoms and quality of life.

Lung Transplant

Due to the chronic nature of this disease some patients may be qualified for lung transplantation. COPD is considered as the most common indication for lung transplantation[1].

Indications

  • BODE index of 7 to 10 or at least 1 of the following:
1-History of hospitalization for exacerbation associated with acute hypercapnia (P co2 exceeding 50 mmHg)
2-Pulmonary hypertension or cor pulmonale, or both, despite oxygen therapy
3-FEV1 < 20% and either DlCO < 20% or homogeneous distribution of emphysema[2]

Contraindications

1-Recent malignancy (other than nonmelanoma skin cancer)
2-Active infection with hepatitis B or C virus associated with histologic evidence of significant liver damage
3-Active or recent cigarette smoking, drug abuse, or alcohol abuse
4-Severe psychiatric illness
5-Repeated noncompliance with medical care
6-Absence of a consistent and reliable social support network
7-HIV infection(in some centers AIDS is considered as absolute contraindication)



References

  1. Yusen RD, Edwards LB, Kucheryavaya AY, Benden C, Dipchand AI, Dobbels F, Goldfarb SB, Levvey BJ, Lund LH, Meiser B, Stehlik J (2014). "The registry of the International Society for Heart and Lung Transplantation: thirty-first adult lung and heart-lung transplant report--2014; focus theme: retransplantation". J. Heart Lung Transplant. 33 (10): 1009–24. doi:10.1016/j.healun.2014.08.004. PMID 25242125.
  2. Kreider M, Hadjiliadis D, Kotloff RM (2011). "Candidate selection, timing of listing, and choice of procedure for lung transplantation". Clin. Chest Med. 32 (2): 199–211. doi:10.1016/j.ccm.2011.02.001. PMID 21511083.