Chondrosarcoma X Ray

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X Ray

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]


On x-ray, chondrosarcoma is characterized by lytic lesion, intralesional calcification, endosteal scalloping, and cortical remodeling.

X Ray


  • AP and lateral view of the affected bone is needed.


  • An x-ray may be helpful in the diagnosis of chondrosarcoma. Findings on an x-ray suggestive of chondrosarcoma include: :[1][2][3][4]
    • Lytic or blastic lesion
    • Intralesional calcification classicaly called as popcorn calcification.
    • Endosteal scalloping affecting more than two thirds of the cortical thickness
    • Moth eaten appearance or permeative appearance in higher grade tumors.
    • Cortical remodeling, thickening and periosteal reaction seen in mesenchymal chondrosarcoma.
    • These findings are useful in distinguishing between an enchondroma and low grade chondrosarcoma.
    • De-differentiated chondrosarcomas radiographically show a lower grade chondroid lesion with superimposed highly destructive area consistent with the high grade transformed dedifferentiated chondrosarcoma.
Xray of knee showing chondrosarcoma of distal femur.Source: Case courtesy of Dr Domenico Nicoletti,, rID: 30655


  1. Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
  2. Czerniak, Bogdan (2016). Dorfman and Czerniak's bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.
  3. Marco RA, Gitelis S, Brebach GT, Healey JH (2000). "Cartilage tumors: evaluation and treatment". J Am Acad Orthop Surg. 8 (5): 292–304. PMID 11029557.
  4. Frassica FJ, Unni KK, Beabout JW, Sim FH (1986). "Dedifferentiated chondrosarcoma. A report of the clinicopathological features and treatment of seventy-eight cases". J Bone Joint Surg Am. 68 (8): 1197–205. PMID 3021775.

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