Chondrosarcoma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

Overview

On MRI, chondrosarcoma is characterized by low to intermediate signal on T1, very high intensity in calcified portions on T2, and moderate to intense contrast enhancement on T1 contrast.

MRI

MRI findings of chondrosarcoma include:[1][2][3][4]

  • T1 image:
  • Low to intermediate signal.
  • Iso- to slightly hyperintense signal of muscle.
  • T2 image:
  • Very high intensity in non-mineralised or calcified portions.
  • T1 C+ (Gd) image:
  • Most demonstrate heterogeneous moderate to intense contrast enhancement.
  • Enhancement can be septal and peripheral rim-like corresponding to fibrovascular septation between lobules of hyaline cartilage.
MRI of knee showing chondrosarcoma of distal femur.Source: Case courtesy of Dr Domenico Nicoletti, Radiopaedia.org, rID: 30655


References

  1. Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
  2. Czerniak, Bogdan (2016). Dorfman and Czerniak's bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.
  3. Frassica FJ, Unni KK, Beabout JW, Sim FH (1986). "Dedifferentiated chondrosarcoma. A report of the clinicopathological features and treatment of seventy-eight cases". J Bone Joint Surg Am. 68 (8): 1197–205. PMID 3021775.
  4. Björnsson J, McLeod RA, Unni KK, Ilstrup DM, Pritchard DJ (1998). "Primary chondrosarcoma of long bones and limb girdles". Cancer. 83 (10): 2105–19. PMID 9827715.


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