Chickenpox laboratory findings

Revision as of 01:19, 17 August 2017 by Skazmi (talk | contribs)
Jump to navigation Jump to search

Chickenpox Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Chickenpox from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT scan

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Chickenpox laboratory findings On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Chickenpox laboratory findings

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Chickenpox laboratory findings

CDC on Chickenpox laboratory findings

Chickenpox laboratory findings in the news

Blogs on Chickenpox laboratory findings

Directions to Hospitals Treating Chickenpox

Risk calculators and risk factors for Chickenpox laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

Overview

The laboratory findings of chickenpox include blood tests that can be done to identify the response to acute infection (IgM) or previous infection and subsequent immunity (IgG). Prenatal diagnosis of fetal varicella infection can be performed using ultrasound at 5 weeks following primary maternal infection. A PCR test of the mother's amniotic fluid can also be performed, though the risk of spontaneous abortion due to the amniocentesis procedure is higher than the risk of the baby developing fetal varicella syndrome.

Laboratory Findings

Laboratory tests that are shown to be useful for the diagnosis of chickenpox include:

Antibody Testing

IgM

  • It can be detected within 1-2 weeks post exposure.
  • The levels of IgM antibodies rise for a short period of time and then fall below detectable levels.
  • Post-Infection, the IgM levels rise only when the latent VZV is reactivated.

IgG

  • IgG antibodies are produced several weeks after the initial exposure.
  • IgG levels rise during active infection and then the levels become stable as the VZV infection gets resolves and as the virus gets inactivated.

Viral detection

VZV DNA testing

Direct Fluorescent Antibody (DFA)

VZV culture

Microscopic Findings

References

  1. 1.0 1.1 Gershon AA, Breuer J, Cohen JI, Cohrs RJ, Gershon MD, Gilden D; et al. (2015). "Varicella zoster virus infection". Nat Rev Dis Primers. 1: 15016. doi:10.1038/nrdp.2015.16. PMC 5381807. PMID 27188665.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 "Public Health Image Library (PHIL)".


Template:WikiDoc Sources