Cellulitis resident survival guide

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Synonyms and keywords:

Overview

Causes

Life Threatening Causes

No known life-threatening causes are included.

Common Causes

The cellulitis is bacterial in origin caused by invasion of bacteria through the skin barrier. The common causes are:

Diagnosis

Shown below is an algorithm summarizing the diagnosis of cellulitis according to the Infectious Diseases Society of America guidelines.

 
 
 
Patients presents with clinical symptoms suggestive of cellulitis, i.e.
  • erythema
  • edema
  • warmth
  • swollen regional lymph nodes
  • involvement of one limb.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Perform compression Doppler ultrasound of the limb and D-dimers level
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Positive
 
Negative
 
 
 
 
 
 
 
 
 
 
 
 
likely Deep venous thrombosis (DVT)
 
DVT unlikely. High clinical suspicion for cellulitis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Assess levels of inflammatory markers
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Raised ESR, CRP and leukocytosis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Does patient have any signs of rapidly progressive or systemic infection?
  • Body temperature>101.5 degrees Fahrenheit, chills, headache, and fatigue
  • Signs of sepsis. i.e. hypotension and heart rate>100bpm
  • Patient develops rapidly progressive symptoms like bullae, vesicles, petechiae, crepitus
  • Patient has low immunity (i.e. infants and elderly patients)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Perform the following tests:
  • Debridement of wound with culture of the specimen
  • Blood culture
  • Radiographic tests to evaluate deep tissue infection

Treatment

Shown below is an algorithm summarizing the treatment of [[disease name]] according the the [...] guidelines.

 
 
 
 
 
 
 
Is the cellulitis having a purulent discharge?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Are there any of the following clinical signs?
  • Systemic toxicity (fever, hypotension, and tachycardia)
  • Presence of an indwelling device (pacemaker, vascular graft)
  • Patient is on extremes of age
  • Major comorbid conditions
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Initiate intravenous antibiotic therapy. The coverage of the micro-organisms is determined by:
  • Oral or peri-rectal ulcers
  • Pressure ulcer with draining abscess
  • Necrosis of overlying skin
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
No
 
 
 
 
 
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Do's

  • The content in this section is in bullet points.

Don'ts

  • The content in this section is in bullet points.

References