Cefadroxil: Difference between revisions
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==Overview== | ==Overview== | ||
Cefadroxil (formerly trademarked as Duricef) is a broad-spectrum antibiotic of | |||
the [[cephalosporin]] type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic. | Cefadroxil (formerly trademarked as Duricef) is a broad-spectrum antibiotic of the [[cephalosporin]] type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic. | ||
==Category== | ==Category== | ||
Cephalosporin,First-Generation | Cephalosporin, First-Generation | ||
==US Brand Names== | ==US Brand Names== | ||
DURICEF<sup>®</sup> | DURICEF<sup>®</sup> | ||
==FDA Package Insert== | ==FDA Package Insert== | ||
'''[[Cefadroxil description|Description]]''' | |||
''' [[Cefadroxil description|Description]]''' | |||
'''| [[Cefadroxil clinical pharmacology|Clinical Pharmacology]]''' | '''| [[Cefadroxil clinical pharmacology|Clinical Pharmacology]]''' | ||
'''| [[Cefadroxil microbiology|Microbiology]]''' | '''| [[Cefadroxil microbiology|Microbiology]]''' | ||
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==Mechanism of Action== | ==Mechanism of Action== | ||
Cefadroxil belongs to the first-genaration [[Cephalosporins]].[[Cephalosporins]] are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as penicillins). [[Cephalosporins]] disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin binding | Cefadroxil belongs to the first-genaration [[Cephalosporins]].[[Cephalosporins]] are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as penicillins). [[Cephalosporins]] disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as [[penicillin-binding protein]]s (PBPs). | ||
==References== | ==References== | ||
Revision as of 23:26, 5 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Cefadroxil (formerly trademarked as Duricef) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic.
Category
Cephalosporin, First-Generation
US Brand Names
DURICEF®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
Cefadroxil belongs to the first-genaration Cephalosporins.Cephalosporins are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as penicillins). Cephalosporins disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin-binding proteins (PBPs).