Caspase 5

Jump to navigation Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
caspase 5, apoptosis-related cysteine peptidase
Identifiers
SymbolCASP5
Alt. symbolsICE(rel)III, ICH3
Entrez838
HUGO1506
OMIM602665
RefSeqNM_004347
UniProtP51878
Other data
EC number3.4.22.58
LocusChr. 11 q22.2-q22.3

Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.[1]

See also

References

  1. Martinon F, Tschopp J (2007). "Inflammatory caspases and inflammasomes: master switches of inflammation". Cell Death Differ. 14 (1): 10–22. doi:10.1038/sj.cdd.4402038. PMID 16977329.

External links

  • The MEROPS online database for peptidases and their inhibitors: C14.008