Cardiac allograft vasculopathy prevention
Cardiac allograft vasculopathy Microchapters |
Differentiating Cardiac allograft vasculopathy from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Cardiac allograft vasculopathy prevention On the Web |
American Roentgen Ray Society Images of Cardiac allograft vasculopathy prevention |
Directions to Hospitals Treating Cardiac allograft vasculopathy |
Risk calculators and risk factors for Cardiac allograft vasculopathy prevention |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2] Raviteja Guddeti, M.B.B.S. [3]
Overview
Prevention
As the pathogenesis of CAV consists of both immunological and non-immunological insults, it has been suggested that preventative strategies should consist of control of risk factors for CAV and optimal immunosuppressive therapy. However, the best preventative strategy to delay development of CAV is yet to be determined.
Optimization of Immunosuppressive Therapy
Options for immunosuppressive therapy for prevention of CAV include [1]:
- Calcineurin inhibitors, such as
- Sirolimus (Rapamycin)
- Everolimus, a Rapamycin derivative
- Corticosteroids
- Azathioprine
- Mycophenolate mofetil
Calcineurin inhibitors
References
- ↑ Mehra MR (2006). "Contemporary concepts in prevention and treatment of cardiac allograft vasculopathy". Am J Transplant. 6 (6): 1248–56. doi:10.1111/j.1600-6143.2006.01314.x. PMID 16686747.