Carbocisteine: Difference between revisions

Jump to navigation Jump to search
m (Protected "Carbocisteine": Protecting pages from unwanted edits ([edit=sysop] (indefinite) [move=sysop] (indefinite)))
 
mNo edit summary
 
(6 intermediate revisions by one other user not shown)
Line 1: Line 1:
{{drugbox
: [[File:Carbocystiene Wiki Str.png|right|300px]]
| IUPAC_name        = 2-amino-3-(carboxymethylsulfanyl)propanoic acid
__NOTOC__
| image            = carbocisteine.png
{{SI}}
| CAS_number        =
{{CMG}}
| ATC_prefix        = R05
==Overview==
| ATC_suffix        = CB03
'''Carbocisteine''' is a [[mucolytic]] that reduces the viscosity of sputum and so can be used to help relieve the symptoms of [[chronic obstructive pulmonary disorder]] (COPD) and [[bronchiectasis]] by allowing the sufferer to bring up [[sputum]] more easily. Carbocisteine should not be used with [[antitussive]]s (cough suppressants) or medicines that dry up bronchial secretions.
| PubChem          = 1080
| DrugBank          =
| C=5|H=9|N=1|O=4|S=1
| molecular_weight  = 179.195 g/mol
| bioavailability  =
| protein_bound    =
| metabolism        =
| elimination_half-life =
| excretion        =
| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      =  <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA          =  <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK          =  <!-- GSL        / P      / POM / CD / Class A, B, C -->
| legal_US          =  <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status      =
| routes_of_administration =
}}
'''Carbocisteine''' is a [[mucolytic]] that can be used to help relieve the symptoms of Chronic Obstructive Pulmonary Disorder [[COPD]] and [[bronchiectasis]] by allowing the sufferer to bring up [[sputum]] more easily.


{{pharmacology-stub}}
Carbocisteine is produced by [[alkylation]] of [[cysteine]] with [[chloroacetic acid]].<ref>Karlheinz Drauz, Ian Grayson, Axel Kleemann, Hans-Peter Krimmer, Wolfgang Leuchtenberger, Christoph Weckbecker “Amino Acids” in ''Ullmann's Encyclopedia of Industrial Chemistry'', 2007, Wiley-VCH, Weinheim. {{DOI|10.1002/14356007.a02_057.pub2}}</ref>


==Trade names==
*Fluidol, Humotusin: Romania
*Rhinathiol: Bulgaria, Congo, Hong Kong, Hungary, Latvia, Lithuania, Malaysia, Oman, Romania, Singapore, South Korea, Switzerland, Taiwan, Thailand, Tunisia, and Vietnam<ref>http://www.drugs.com/international/rhinathiol.html</ref>
*Mucodyne: United Kingdom, India, Ireland, Japan, Netherlands, Serbia.
*Mucoral: Portugal
*Mucosol: Egypt
*Solmux, Loviscol: Philippines
==References==
{{reflist|2}}


{{Cough and cold preparations}}
{{Cough and cold preparations}}


[[Category:Antitussives]]
[[Category:Drug]]
[[Category:Amino acids]]
[[Category:Dicarboxylic acids]]
[[Category:Expectorants]]
[[Category:Thioethers]]
[[Category:Thioethers]]
[[Category:Amino acid derivatives]]

Latest revision as of 16:15, 8 April 2015

WikiDoc Resources for Carbocisteine

Articles

Most recent articles on Carbocisteine

Most cited articles on Carbocisteine

Review articles on Carbocisteine

Articles on Carbocisteine in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Carbocisteine

Images of Carbocisteine

Photos of Carbocisteine

Podcasts & MP3s on Carbocisteine

Videos on Carbocisteine

Evidence Based Medicine

Cochrane Collaboration on Carbocisteine

Bandolier on Carbocisteine

TRIP on Carbocisteine

Clinical Trials

Ongoing Trials on Carbocisteine at Clinical Trials.gov

Trial results on Carbocisteine

Clinical Trials on Carbocisteine at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Carbocisteine

NICE Guidance on Carbocisteine

NHS PRODIGY Guidance

FDA on Carbocisteine

CDC on Carbocisteine

Books

Books on Carbocisteine

News

Carbocisteine in the news

Be alerted to news on Carbocisteine

News trends on Carbocisteine

Commentary

Blogs on Carbocisteine

Definitions

Definitions of Carbocisteine

Patient Resources / Community

Patient resources on Carbocisteine

Discussion groups on Carbocisteine

Patient Handouts on Carbocisteine

Directions to Hospitals Treating Carbocisteine

Risk calculators and risk factors for Carbocisteine

Healthcare Provider Resources

Symptoms of Carbocisteine

Causes & Risk Factors for Carbocisteine

Diagnostic studies for Carbocisteine

Treatment of Carbocisteine

Continuing Medical Education (CME)

CME Programs on Carbocisteine

International

Carbocisteine en Espanol

Carbocisteine en Francais

Business

Carbocisteine in the Marketplace

Patents on Carbocisteine

Experimental / Informatics

List of terms related to Carbocisteine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Carbocisteine is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.

Carbocisteine is produced by alkylation of cysteine with chloroacetic acid.[1]

Trade names

  • Fluidol, Humotusin: Romania
  • Rhinathiol: Bulgaria, Congo, Hong Kong, Hungary, Latvia, Lithuania, Malaysia, Oman, Romania, Singapore, South Korea, Switzerland, Taiwan, Thailand, Tunisia, and Vietnam[2]
  • Mucodyne: United Kingdom, India, Ireland, Japan, Netherlands, Serbia.
  • Mucoral: Portugal
  • Mucosol: Egypt
  • Solmux, Loviscol: Philippines

References

  1. Karlheinz Drauz, Ian Grayson, Axel Kleemann, Hans-Peter Krimmer, Wolfgang Leuchtenberger, Christoph Weckbecker “Amino Acids” in Ullmann's Encyclopedia of Industrial Chemistry, 2007, Wiley-VCH, Weinheim. doi:10.1002/14356007.a02_057.pub2
  2. http://www.drugs.com/international/rhinathiol.html

Template:Cough and cold preparations