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** All procedures that may produce [[aerosols]], or involve high concentrations or large volumes should be conducted in a biological safety cabinet (BSC)
** All procedures that may produce [[aerosols]], or involve high concentrations or large volumes should be conducted in a biological safety cabinet (BSC)
** The use of [[Needle|needles]], [[Syringe|syringes]], and other sharp objects should be strictly limited. Additional precautions should be considered with work involving animals or large scale activities
** The use of [[Needle|needles]], [[Syringe|syringes]], and other sharp objects should be strictly limited. Additional precautions should be considered with work involving animals or large scale activities
====Public policy====
According to a modeling study
<ref name="KooCook2020">{{cite journal|last1=Koo|first1=Joel R|last2=Cook|first2=Alex R|last3=Park|first3=Minah|last4=Sun|first4=Yinxiaohe|last5=Sun|first5=Haoyang|last6=Lim|first6=Jue Tao|last7=Tam|first7=Clarence|last8=Dickens|first8=Borame L|title=Interventions to mitigate early spread of SARS-CoV-2 in Singapore: a modelling study|journal=The Lancet Infectious Diseases|year=2020|issn=14733099|doi=10.1016/S1473-3099(20)30162-6}}</ref>:
"Implementing the combined intervention of
* quarantining infected individuals and their family members,
* workplace distancing, and
* school closure once community transmission has been detected
...could substantially reduce the number of SARS-CoV-2 infections."
Similar findings have been modeled by the Medical Research Council (MRC) Centre for Global Infectious Disease Analysis and WHO Collaborating Centre for Infectious Disease Modelling
<ref>{{Cite conference| last1 = Ferguson| first1 = N.| last2 = Laydon| first2 = D.| last3 = Nedjati Gilani| first3 = G.| last4 = Imai| first4 = N.| last5 = Ainslie| first5 = K.| last6 = Baguelin| first6 = M.| last7 = Bhatia| first7 = S.| last8 = Boonyasiri| first8 = A.| last9 = Cucunuba Perez| first9 = Zulma| last10 = Cuomo-Dannenburg| first10 = G.| last11 = Dighe| first11 = A.| last12 = Dorigatti| first12 = I.| last13 = Fu| first13 = H.| last14 = Gaythorpe| first14 = K.| last15 = Green| first15 = W.| last16 = Hamlet| first16 = A.| last17 = Hinsley| first17 = W.| last18 = Okell| first18 = L.| last19 = Van Elsland| first19 = S.| last20 = Thompson| first20 = H.| last21 = Verity| first21 = R.| last22 = Volz| first22 = E.| last23 = Wang| first23 = H.| last24 = Wang| first24 = Y.| last25 = Walker| first25 = P.| last26 = Winskill| first26 = P.| last27 = Whittaker| first27 = C.| last28 = Donnelly| first28 = C.| last29 = Riley| first29 = S.| last30 = Ghani| first30 = A.| title = Report 9: Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand| accessdate = 2020-03-25| date = 2020-03-16| url = http://spiral.imperial.ac.uk/handle/10044/1/77482}}</ref>.
Other preliminary research is available<ref name="LaiRuktanonchai2020">{{cite journal|last1=Lai|first1=Shengjie|last2=Ruktanonchai|first2=Nick W|last3=Zhou|first3=Liangcai|last4=Prosper|first4=Olivia|last5=Luo|first5=Wei|last6=Floyd|first6=Jessica R|last7=Wesolowski|first7=Amy|last8=Santillana|first8=Mauricio|last9=Zhang|first9=Chi|last10=Du|first10=Xiangjun|last11=Yu|first11=Hongjie|last12=Tatem|first12=Andrew J|year=2020|doi=10.1101/2020.03.03.20029843}}</ref>.


=== Handling and Storage ===
=== Handling and Storage ===

Revision as of 04:59, 30 March 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overiew

There is currently no vaccine to prevent 2019-nCoV infection. The best way to prevent infection is to avoid being exposed to this virus. The fact that it is currently flu and respiratory disease season, CDC recommends getting a flu vaccine, taking everyday preventive actions to help stop the spread of germs, and taking flu antivirals if prescribed. Healthcare providers are advised to be on the look-out for people who recently traveled from China and have fever and respiratory symptoms.

Primary Prevention

Exposure Control

2019-nCoV

There is currently no vaccine to prevent 2019-nCoV infection. The best way to prevent infection is to avoid being exposed to this virus. The following practices should be adopted for infection control:[1]

  • Protective clothing:
    • Lab coats, gloves when direct skin contact with infected materials or animals is unavoidable
    • Eye protection must be used where there is a known or potential risk of exposure to splashes
  • Miscellaneous:
    • All procedures that may produce aerosols, or involve high concentrations or large volumes should be conducted in a biological safety cabinet (BSC)
    • The use of needles, syringes, and other sharp objects should be strictly limited. Additional precautions should be considered with work involving animals or large scale activities

Public policy

According to a modeling study [2]: "Implementing the combined intervention of

  • quarantining infected individuals and their family members,
  • workplace distancing, and
  • school closure once community transmission has been detected

...could substantially reduce the number of SARS-CoV-2 infections."

Similar findings have been modeled by the Medical Research Council (MRC) Centre for Global Infectious Disease Analysis and WHO Collaborating Centre for Infectious Disease Modelling [3].

Other preliminary research is available[4].

Handling and Storage

CDC Recommendations Regarding 2019-nCoV Infection

  • While the immediate risk of this new virus to the American public is believed to be low at this time, everyone can do their part to help in responding to this emerging public health threat:[5]

References

  1. https://www.cdc.gov/coronavirus/2019-ncov/index.html. Missing or empty |title= (help)
  2. Koo, Joel R; Cook, Alex R; Park, Minah; Sun, Yinxiaohe; Sun, Haoyang; Lim, Jue Tao; Tam, Clarence; Dickens, Borame L (2020). "Interventions to mitigate early spread of SARS-CoV-2 in Singapore: a modelling study". The Lancet Infectious Diseases. doi:10.1016/S1473-3099(20)30162-6. ISSN 1473-3099.
  3. Ferguson, N.; Laydon, D.; Nedjati Gilani, G.; Imai, N.; Ainslie, K.; Baguelin, M.; Bhatia, S.; Boonyasiri, A.; Cucunuba Perez, Zulma; Cuomo-Dannenburg, G.; Dighe, A.; Dorigatti, I.; Fu, H.; Gaythorpe, K.; Green, W.; Hamlet, A.; Hinsley, W.; Okell, L.; Van Elsland, S.; Thompson, H.; Verity, R.; Volz, E.; Wang, H.; Wang, Y.; Walker, P.; Winskill, P.; Whittaker, C.; Donnelly, C.; Riley, S.; Ghani, A. (2020-03-16). Report 9: Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand. Retrieved 2020-03-25.
  4. Lai, Shengjie; Ruktanonchai, Nick W; Zhou, Liangcai; Prosper, Olivia; Luo, Wei; Floyd, Jessica R; Wesolowski, Amy; Santillana, Mauricio; Zhang, Chi; Du, Xiangjun; Yu, Hongjie; Tatem, Andrew J (2020). doi:10.1101/2020.03.03.20029843. Missing or empty |title= (help)
  5. https://www.cdc.gov/coronavirus/2019-nCoV/summary.html. Missing or empty |title= (help)