CGS-9896: Difference between revisions

Jump to navigation Jump to search
m (Protected "CGS-9896": Robot: Protecting all pages from category Drug ([edit=sysop] (indefinite) [move=sysop] (indefinite)))
 
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
Line 37: Line 37:


== References ==
== References ==
<references />
{{reflist|2}}





Latest revision as of 15:04, 4 September 2012

CGS-9896
File:CGS-9896.svg
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC16H10ClN3O
Molar mass295.7231 g/mol
3D model (JSmol)

CGS-9896 is an anxiolytic drug used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1]

CGS-9896 is a benzodiazepine receptor partial agonist, which produces long-lasting anxiolytic and anticonvulsant effects in animal studies, but does not produce sedative effects.[2][3] It also increases appetite,[4] and reduces the development of gastrointestinal ulcers following chronic stress.[5]


Template:Pharmacology-stub


References

  1. Leidenheimer NJ, Schechter MD. Discriminative stimulus properties of CGS 9896: interactions within the GABA/benzodiazepine receptor complex. Pharmacology, Biochemistry and Behaviour. 1988 Oct;31(2):249-54. PMID 2854261
  2. Bernasconi R, Marescaux C, Vergnes M, Klebs K, Klein M, Martin P, Portet C, Maitre L, Schmutz M. Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models. Journal of Neural Transmission. 1988;71(1):11-27. PMID 3343593
  3. Rump S, Raszewski W, Gidynska T, Galecka E. Effects of CGS 9896 in acute experimental intoxication with fluostigmine. Archives of Toxicology. 1990;64(5):412-3. PMID 2206111
  4. Chen SW, Davies MF, Loew GH. Food palatability and hunger modulated effects of CGS 9896 and CGS 8216 on food intake. Pharmacology, Biochemistry and Behaviour. 1995 Jun-Jul;51(2-3):499-503. PMID 7667375
  5. Najim RA, Karim KH. Effect of CGS 9896 on stress-induced gastric ulcer in rat. Clinical and Experimental Pharmacology and Physiology. 1990 Feb;17(2):157-161. PMID 2109664


Template:Anxiolytics Template:WikiDoc Sources