CD244

Jump to navigation Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene.[1] It is also known as Natural Killer Cell Receptor 2B4[2]

This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[3] CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.[4]


See also

References

  1. "Entrez Gene: CD244 CD244 molecule, natural killer cell receptor 2B4".
  2. Online Mendelian Inheritance in Man (OMIM) 605554
  3. "CD244 molecule, natural killer cell receptor 2B4 ( Homo sapiens (human) )".
  4. PMID 25643613

Further reading

External links