C9orf64

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

C9orf64 (Chromosome 9 open reading frame 64) is a gene located on chromosome 9, that in humans encodes the protein LOC84267. The function and biological process of protein LOC84267 is not well understood by the scientific community. The most common mRNA contains 4 coding exons. C9orf64 has been found in 5 different splice variants.

Protein

LOC84267 is 341 amino acids long with a molecular weight of 39,029 Daltons and an isoelectric point of 5.61. It is a member of the DUF2419 superfamily. The DUF position on the human protein is from amino acid 53 to 341. Bioinformatic tools at ExPASy predicted a second peroxisomal targeting signal.

Gene locus

C9orf64 is located on chromosome 9q21.32. The genes closest to C9orf64 on the long arm of chromosome 9 include GKAP1, KIF27, HNRNPK, RMI1, and a MicroRNA MIR7-1.

Homology

C9orf64 is only found in eukaryotes. Orthologs have been found from primates to fungi and plants.

External links

• Human C9orf64 genome location and C9orf64 gene details page in the UCSC Genome Browser.

Further reading

• Cai LY, Abe M, Izumi S, Imura M, Yasugi T, Ushijima T (2007). "Identification of PRTFDC1 silencing and aberrant promoter methylation of GPR150, ITGA8 and HOXD11 in ovarian cancers". Life Sciences. 80 (16): 1458–65. doi:10.1016/j.lfs.2007.01.015. PMID 17303177.
• Sweetser DA, Peniket AJ, Haaland C, Blomberg AA, Zhang Y, Zaidi ST, Dayyani F, Zhao Z, Heerema NA, Boultwood J, Dewald GW, Paietta E, Slovak ML, Willman CL, Wainscoat JS, Bernstein ID, Daly SB (2005). "Delineation of the minimal commonly deleted segment and identification of candidate tumor-suppressor genes in del(9q) acute myeloid leukemia". Genes, Chromosomes and Cancer. 44 (3): 279–91. doi:10.1002/gcc.20236. PMID 16015647.