Burn future or investigational therapies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eman Alademi, M.D.[2]

Overview

Burn future or investigation therapies

A primarily topical therapy and topical therapy

antibiotics

fluid resuscitation

skin excision and grafting

respiratory and metabolic care and nutrition.

The use of systemic antibiotics and topical silver therapy greatly reduced sepsis related mortality.

This along with the advent of antiseptic surgical techniques, burn depth classification and skin grafting allowed the excision and coverage of full-thickness burns which resulted in greatly improved survival rates. Advancements in the methods of assessing the surface area of burns paved way for more accurate fluid resuscitation, minimizing the effects of shock and avoiding fluid over-loading.

metabolic care,

nutritional support and care of inhalation injuries further improved the outcome of burn patients.

burn care such as the use of cell and pharma-logical therapies.[1]


You may need one or more of the following procedures:

  • Breathing assistance. If you've been burned on the face or neck, your throat may swell shut. If that appears likely, your doctor may insert a tube down your windpipe (trachea) to keep oxygen supplied to your lungs.
  • Feeding tube. People with extensive burns or who are undernourished may need nutritional support. Your doctor may thread a feeding tube through your nose to your stomach.
  • Easing blood flow around the wound. If a burn scab (eschar) goes completely around a limb, it can tighten and cut off the blood circulation. An eschar that goes completely around the chest can make it difficult to breathe. Your doctor may cut the eschar to relieve this pressure.
  • Skin grafts. A skin graft is a surgical procedure in which sections of your own healthy skin are used to replace the scar tissue caused by deep burns. Donor skin from deceased donors or pigs can be used as a temporary solution.
  • Plastic surgery. Plastic surgery (reconstruction) can improve the appearance of burn scars and increase the flexibility of joints affected by scarring.

References

  1. Moiemen, NaiemS; Lee, KwangChear; Joory, Kavita (2014). "History of burns: The past, present and the future". Burns & Trauma. 2 (4): 169. doi:10.4103/2321-3868.143620. ISSN 2321-3868.

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