Burkitt's lymphoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2], Kamal Akbar, M.D.[3]

Overview

Burkitt's lymphoma is a common disease that tends to affect children or young adults. Males are more commonly affected with Burkitt's lymphoma compared to females. Burkitt's lymphoma usually affects individuals of the African race.

Epidemiology and Demographics

Incidence

  • The incidence of is approximately 3 to 6 cases per 100,000 children per year for endemic and 0.02 cases per 100,000 people for sporadic burkitt's lymphoma[1][2]

Age

  • Burkitt's lymphoma is a common disease that tends to affect children or young adults. The median age at diagnosis is 8 years[3]

Gender

  • Males are more commonly affected with Burkitt's lymphoma than females. The Male to Female ratio is approximately 4 to 1[4]

Race

  • Burkitt's lymphoma usually affects individuals of the African race[4]

Region

  • The majority of Burkitt's lymphoma cases are reported in equitorial Africa[5]

References

  1. Magrath, Ian (2012). "Epidemiology: clues to the pathogenesis of Burkitt lymphoma". British Journal of Haematology. 156 (6): 744–756. doi:10.1111/j.1365-2141.2011.09013.x. ISSN 0007-1048.
  2. Sant, M.; Allemani, C.; Tereanu, C.; De Angelis, R.; Capocaccia, R.; Visser, O.; Marcos-Gragera, R.; Maynadie, M.; Simonetti, A.; Lutz, J.-M.; Berrino, F. (2010). "Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project". Blood. 116 (19): 3724–3734. doi:10.1182/blood-2010-05-282632. ISSN 0006-4971.
  3. Dozzo M, Carobolante F, Donisi PM, Scattolin A, Maino E, Sancetta R; et al. (2017). "Burkitt lymphoma in adolescents and young adults: management challenges". Adolesc Health Med Ther. 8: 11–29. doi:10.2147/AHMT.S94170. PMC 5207020. PMID 28096698.
  4. 4.0 4.1 Boerma EG, van Imhoff GW, Appel IM, Veeger NJ, Kluin PM, Kluin-Nelemans JC (2004). "Gender and age-related differences in Burkitt lymphoma--epidemiological and clinical data from The Netherlands". Eur J Cancer. 40 (18): 2781–7. doi:10.1016/j.ejca.2004.09.004. PMID 15571961.
  5. Orem J, Mbidde EK, Lambert B, de Sanjose S, Weiderpass E (2007). "Burkitt's lymphoma in Africa, a review of the epidemiology and etiology". Afr Health Sci. 7 (3): 166–75. doi:10.5555/afhs.2007.7.3.166. PMC 2269718. PMID 18052871.


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