Burkitt's lymphoma (patient information): Difference between revisions

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'''Editor-in-Chief:''' [[C. Michael Gibson]], M.S.,M.D. [mailto:mgibson@perfuse.org]  Phone:617-632-7753; '''Associate Editor-In-Chief:''' Jinhui Wu, M.D.
'''Editor-in-Chief:''' [[C. Michael Gibson]], M.S.,M.D. [mailto:mgibson@perfuse.org]  Phone:617-632-7753; '''Associate Editor(s)-In-Chief:''' Jinhui Wu, M.D.; [[Lakshmi Gopalakrishnan]], M.B.B.S.


==Overview==
==Overview==
Burkitt lymphoma is one kind of [[B-cell lymphoma]], also one type of [[Non-Hodgkin lymphoma]]. It is named after the doctor who first described this disease in African children and young adults. Its cells are medium sized. Close to 90% of patients are male, and the average age is about 30. It is a very fast-growing lymphoma and over half of patients can be cured by intensive chemotherapy.
Burkitt lymphoma is one kind of [[B-cell lymphoma]], also one type of [[Non-Hodgkin lymphoma]]. It is named after the doctor who first described this disease in African children and young adults. Its cells are medium sized. Close to 90% of patients are male, and the average age is about 30. It is a very fast-growing lymphoma and over half of patients can be cured by intensive chemotherapy.
==What are the symptoms of Burkitt's lymphoma==
*Burkitt lymphoma may first be noticed as a swelling of the lymph nodes (glands) in the neck, groin, or under the arm. These swollen lymph nodes are often painless, but can grow very rapidly.
*In the types commonly seen in the United States, the cancer usually starts in the belly area (abdomen). The disease can also start in the ovaries, testes, brain, and spinal fluid.
*Symptoms include:
:*Lymph nodes that grow together to form a lump
:*Nontender lymph nodes
:*Rapid growth of the lymph nodes
:*Unexplained swollen lymph nodes
==What causes Burkitt's lymphoma==
*Burkitt lymphoma was first discovered in children in certain parts of Africa, but it also occurs in the United States.
*The African type of Burkitt lymphoma is closely associated with the '''Epstein-Barr virus (EBV)''', the main cause of [[infectious mononucleosis]]. The North American form of Burkitt lymphoma is not linked to EBV.
*Burkitt lymphoma is most often seen in males.
==How to know you have a Burkitt's lymphoma==
*Bone marrow biopsy
*Chest x-ray
*CT scan of the chest, abdomen, and pelvis
*Complete blood count (CBC)
*Examination of the spinal fluid
*Lymph node biopsy
*PET scan
==When to seek urgent medical care==
Call your health care provider if you have symptoms of Burkitt lymphoma.
==Treatment options==
Chemotherapy is used to treat this type of cancer. Commonly used medicines include:
*[[Prednisone]],
*[[Cyclophosphamide]],
*Ifosfamide,
*Vincristine,
*Cytarabine,
*Doxorubicin,
*[[Methotrexate]], and
*Etoposide.


==Where to find medical care for Burkitt lymphoma==  
==Where to find medical care for Burkitt lymphoma==  
[http://maps.google.com/maps?f=q&hl=en&geocode=&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|Burkitt lymphoma}}}}&sll=37.0625,-95.677068&sspn=65.008093,112.148438&ie=UTF8&ll=37.0625,-95.677068&spn=91.690419,149.414063&z=2&source=embed Directions to Hospitals Treating Burkitt lymphoma]  
[http://maps.google.com/maps?f=q&hl=en&geocode=&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|Burkitt lymphoma}}}}&sll=37.0625,-95.677068&sspn=65.008093,112.148438&ie=UTF8&ll=37.0625,-95.677068&spn=91.690419,149.414063&z=2&source=embed Directions to Hospitals Treating Burkitt lymphoma]  
==What to expect (Outlook/Prognosis)==
More than half of those with Burkitt lymphoma can be cured with intensive chemotherapy. The cure rate may be lower if the cancer spreads to the bone marrow or spinal fluid.
==Possible complications==
*Complications of treatment (radiation therapy or chemotherapy)
*Spread of the cancer


==See also==
==See also==
*[[Non-Hodgkin lymphoma (patient information)]]
*[[Non-Hodgkin lymphoma (patient information)]]
*[[B-cell lymphoma (patient information)]]
*[[B-cell lymphoma (patient information)]]
==Sources==
http://www.nlm.nih.gov/medlineplus/ency/article/001308.htm


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[[Category:Hematology patient information]]
[[Category:Hematology patient information]]
[[Category:Oncology patient information]]
[[Category:Oncology patient information]]
[[Category:Mature chapter]]


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Revision as of 03:40, 29 July 2011

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Burkitt's lymphoma
ICD-10 C83.7
ICD-9 200.2
ICD-O: 9687/3
OMIM 113970
DiseasesDB 1784
MeSH D002051

Template:Search infobox

Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Associate Editor(s)-In-Chief: Jinhui Wu, M.D.; Lakshmi Gopalakrishnan, M.B.B.S.

Overview

Burkitt lymphoma is one kind of B-cell lymphoma, also one type of Non-Hodgkin lymphoma. It is named after the doctor who first described this disease in African children and young adults. Its cells are medium sized. Close to 90% of patients are male, and the average age is about 30. It is a very fast-growing lymphoma and over half of patients can be cured by intensive chemotherapy.

What are the symptoms of Burkitt's lymphoma

  • Burkitt lymphoma may first be noticed as a swelling of the lymph nodes (glands) in the neck, groin, or under the arm. These swollen lymph nodes are often painless, but can grow very rapidly.
  • In the types commonly seen in the United States, the cancer usually starts in the belly area (abdomen). The disease can also start in the ovaries, testes, brain, and spinal fluid.
  • Symptoms include:
  • Lymph nodes that grow together to form a lump
  • Nontender lymph nodes
  • Rapid growth of the lymph nodes
  • Unexplained swollen lymph nodes

What causes Burkitt's lymphoma

  • Burkitt lymphoma was first discovered in children in certain parts of Africa, but it also occurs in the United States.
  • The African type of Burkitt lymphoma is closely associated with the Epstein-Barr virus (EBV), the main cause of infectious mononucleosis. The North American form of Burkitt lymphoma is not linked to EBV.
  • Burkitt lymphoma is most often seen in males.

How to know you have a Burkitt's lymphoma

  • Bone marrow biopsy
  • Chest x-ray
  • CT scan of the chest, abdomen, and pelvis
  • Complete blood count (CBC)
  • Examination of the spinal fluid
  • Lymph node biopsy
  • PET scan

When to seek urgent medical care

Call your health care provider if you have symptoms of Burkitt lymphoma.

Treatment options

Chemotherapy is used to treat this type of cancer. Commonly used medicines include:

Where to find medical care for Burkitt lymphoma

Directions to Hospitals Treating Burkitt lymphoma

What to expect (Outlook/Prognosis)

More than half of those with Burkitt lymphoma can be cured with intensive chemotherapy. The cure rate may be lower if the cancer spreads to the bone marrow or spinal fluid.

Possible complications

  • Complications of treatment (radiation therapy or chemotherapy)
  • Spread of the cancer

See also

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/001308.htm

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