Brugada syndrome diagnostic criteria: Difference between revisions
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{{Brugada syndrome}} | {{Brugada syndrome}} | ||
{{CMG}} | {{CMG}} {{AE}} {{S.G.}} | ||
==Overview== | ==Overview== | ||
The diagnosis of brugada syndrome is based upon electrocardiographic and clinical criteria. | The [[diagnosis]] of brugada syndrome is based upon [[Electrocardiogram|electrocardiographic]] and [[clinical]] [[criteria]]. Only the Type I Brugada pattern qualifies as part of the [[Diagnosis|diagnostic]] [[criteria]] for Brugada syndrome. Other [[rhythm]] [[abnormalities]] and [[family]] history are taken into account when making the [[diagnosis]] of Brugada syndrome. | ||
==Diagnostic Criteria | ==Diagnostic Criteria== | ||
*Only the Type I Brugada pattern qualifies as one of the required diagnostic criteria of Brugada syndrome. Type II and Type III EKG patterns do not qualify. Furthermore, the presence of the Type I Brugada pattern is necessary, but is not sufficient to make the [[diagnosis]] of Brugada syndrome. Other [[clinical]] [[criteria]] must be met as well. The [[diagnosis]] of Brugada syndrome requires that the [[criteria]] below be met:<ref>{{cite journal|title=Brugada Syndrome: Report of the Second Consensus Conference|journal=Heart Rhythm|volume=2|issue=4|year=2005|pages=429–440|issn=15475271|doi=10.1016/j.hrthm.2005.01.005}}</ref><ref name="Batchvarov2014">{{cite journal|last1=Batchvarov|first1=Velislav N|title=The Brugada Syndrome – Diagnosis, Clinical Implications and Risk Stratification|journal=European Cardiology Review|volume=9|issue=2|year=2014|pages=82|issn=1758-3756|doi=10.15420/ecr.2014.9.2.82}}</ref><ref name="Antzelevitch2006">{{cite journal|last1=Antzelevitch|first1=Charles|title=Brugada Syndrome|journal=Pacing and Clinical Electrophysiology|volume=29|issue=10|year=2006|pages=1130–1159|issn=0147-8389|doi=10.1111/j.1540-8159.2006.00507.x}}</ref> | |||
Only the Type I Brugada pattern qualifies as one of the required diagnostic criteria of Brugada syndrome. Type II and Type III EKG patterns do not qualify. Furthermore, the presence of the Type I Brugada pattern is necessary, but is not sufficient to make the diagnosis of Brugada | **The presence of Type 1 [[ST-segment elevation]] in more than one right [[precordial]] lead (V<sub>1</sub>-V<sub>3</sub>). Type I Brugada pattern [[ST interval|ST]] [[elevation]] must be observed either spontaneously or following the administration of a [[sodium]] [[Channel blockers|channel blocking]] agent. | ||
**One or more of the following [[Criterion|criteria]] must also be met: | |||
***[[Family history]] of [[sudden cardiac death]] ([[SCD]]) (<45 years old) | |||
***Documented [[ventricular fibrillation]] ([[VF]]) | |||
***[[Polymorphic ventricular tachycardia]] | |||
***Coved-type ECG changes in family members | |||
***Inducibility of [[ventricular tachycardia]] ([[VT]]) with [[programmed electrical stimulation]] (PES) | |||
**The [[patient]] is also diagnosed as having Brugada syndrome when a Type 2 (saddleback pattern) or Type 3 [[ST interval|ST-segment]] elevation is observed in more than one right [[precordial]] lead under baseline conditions that can be converted to the [[diagnostic]] Type 1 Brugada [[pattern]] following administration of a [[sodium]] [[Channel blockers|channel blocker]] and the [[clinical]] [[criteria]] listed above are met as well. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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{{WS}} | |||
[[CME Category::Cardiology]] | |||
[[Category:Electrophysiology]] | [[Category:Electrophysiology]] | ||
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[[Category:Channelopathy]] | [[Category:Channelopathy]] | ||
[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
Latest revision as of 21:53, 2 January 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
The diagnosis of brugada syndrome is based upon electrocardiographic and clinical criteria. Only the Type I Brugada pattern qualifies as part of the diagnostic criteria for Brugada syndrome. Other rhythm abnormalities and family history are taken into account when making the diagnosis of Brugada syndrome.
Diagnostic Criteria
- Only the Type I Brugada pattern qualifies as one of the required diagnostic criteria of Brugada syndrome. Type II and Type III EKG patterns do not qualify. Furthermore, the presence of the Type I Brugada pattern is necessary, but is not sufficient to make the diagnosis of Brugada syndrome. Other clinical criteria must be met as well. The diagnosis of Brugada syndrome requires that the criteria below be met:[1][2][3]
- The presence of Type 1 ST-segment elevation in more than one right precordial lead (V1-V3). Type I Brugada pattern ST elevation must be observed either spontaneously or following the administration of a sodium channel blocking agent.
- One or more of the following criteria must also be met:
- Family history of sudden cardiac death (SCD) (<45 years old)
- Documented ventricular fibrillation (VF)
- Polymorphic ventricular tachycardia
- Coved-type ECG changes in family members
- Inducibility of ventricular tachycardia (VT) with programmed electrical stimulation (PES)
- The patient is also diagnosed as having Brugada syndrome when a Type 2 (saddleback pattern) or Type 3 ST-segment elevation is observed in more than one right precordial lead under baseline conditions that can be converted to the diagnostic Type 1 Brugada pattern following administration of a sodium channel blocker and the clinical criteria listed above are met as well.
References
- ↑ "Brugada Syndrome: Report of the Second Consensus Conference". Heart Rhythm. 2 (4): 429–440. 2005. doi:10.1016/j.hrthm.2005.01.005. ISSN 1547-5271.
- ↑ Batchvarov, Velislav N (2014). "The Brugada Syndrome – Diagnosis, Clinical Implications and Risk Stratification". European Cardiology Review. 9 (2): 82. doi:10.15420/ecr.2014.9.2.82. ISSN 1758-3756.
- ↑ Antzelevitch, Charles (2006). "Brugada Syndrome". Pacing and Clinical Electrophysiology. 29 (10): 1130–1159. doi:10.1111/j.1540-8159.2006.00507.x. ISSN 0147-8389.