Brown-Sequard syndrome

Revision as of 16:51, 2 August 2016 by Irfan Dotani (talk | contribs)
Jump to navigation Jump to search

WikiDoc Resources for Brown-Sequard syndrome

Articles

Most recent articles on Brown-Sequard syndrome

Most cited articles on Brown-Sequard syndrome

Review articles on Brown-Sequard syndrome

Articles on Brown-Sequard syndrome in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Brown-Sequard syndrome

Images of Brown-Sequard syndrome

Photos of Brown-Sequard syndrome

Podcasts & MP3s on Brown-Sequard syndrome

Videos on Brown-Sequard syndrome

Evidence Based Medicine

Cochrane Collaboration on Brown-Sequard syndrome

Bandolier on Brown-Sequard syndrome

TRIP on Brown-Sequard syndrome

Clinical Trials

Ongoing Trials on Brown-Sequard syndrome at Clinical Trials.gov

Trial results on Brown-Sequard syndrome

Clinical Trials on Brown-Sequard syndrome at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Brown-Sequard syndrome

NICE Guidance on Brown-Sequard syndrome

NHS PRODIGY Guidance

FDA on Brown-Sequard syndrome

CDC on Brown-Sequard syndrome

Books

Books on Brown-Sequard syndrome

News

Brown-Sequard syndrome in the news

Be alerted to news on Brown-Sequard syndrome

News trends on Brown-Sequard syndrome

Commentary

Blogs on Brown-Sequard syndrome

Definitions

Definitions of Brown-Sequard syndrome

Patient Resources / Community

Patient resources on Brown-Sequard syndrome

Discussion groups on Brown-Sequard syndrome

Patient Handouts on Brown-Sequard syndrome

Directions to Hospitals Treating Brown-Sequard syndrome

Risk calculators and risk factors for Brown-Sequard syndrome

Healthcare Provider Resources

Symptoms of Brown-Sequard syndrome

Causes & Risk Factors for Brown-Sequard syndrome

Diagnostic studies for Brown-Sequard syndrome

Treatment of Brown-Sequard syndrome

Continuing Medical Education (CME)

CME Programs on Brown-Sequard syndrome

International

Brown-Sequard syndrome en Espanol

Brown-Sequard syndrome en Francais

Business

Brown-Sequard syndrome in the Marketplace

Patents on Brown-Sequard syndrome

Experimental / Informatics

List of terms related to Brown-Sequard syndrome

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Synonyms and keywords: Brown-Séquard's hemiplegia; Brown-Séquard's paralysis

Brown-Sequard syndrome
Brown-Sequard syndrome is bottom diagram
ICD-10 G83.8
ICD-9 344.89
DiseasesDB 31117
MeSH D018437

Overview

'Brown-Séquard syndrome is a loss of motricity (paralysis and ataxia) and sensation caused by the lateral hemisection of the spinal cord. Other synonyms are crossed hemiplegia, hemiparaplegic syndrome, hemiplegia et hemiparaplegia spinalis and spinal hemiparaplegia.

Historical Perspective

It was first described in 1850 by the historically famous British neurologist Charles Édouard Brown-Sequard (1817-1896), who studied the anatomy and physiology of the spinal cord. [1][2] Brown-Sequard was quite a controversial and eccentric figure, and is also known for self-reporting "rejuvinated sexual prowess after eating extracts of monkey testis". The response is now thought to have been a placebo effect, but apparently this was "sufficient to set the field of endocrinology off and running."[3]

Interestingly, many nations claim him as their own, he was the son of an American sea captain and a French woman, living in a British territory. He studied in the US, France, as well as the UK. He described this injury which resulted from caning knives trauma in Mauritius.

Classification

Pathophysiology

The hemisection of the cord results in a lesion of each of the three main neural systems:

As a result of the injury to these three main brain pathways the patient will present with three lesions.

  • The corticospinal lesion produces spastic paralysis on the same side of the body (the loss of moderation by the UMN).
  • The loss of the spinothalamic tract leads to pain and temperature sensation being lost from the contralateral side beginning one or two segments below the lesion. At the lesion site all sensory modalities are lost on the same side, and also an ipsilateral flaccid paralysis.

Causes

Brown-Sequard syndrome may be caused by a spinal cord tumor, trauma (such as a gunshot wound or puncture wound to the neck or back), ischemia (obstruction of a blood vessel), or infectious or inflammatory diseases such as tuberculosis, or multiple sclerosis.

Differentiating Brown-Sequard syndrome from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

References

  1. Template:WhoNamedIt
  2. C.-E. Brown-Séquard: De la transmission croisée des impressions sensitives par la moelle épinière. Comptes rendus de la Société de biologie, (1850)1851, 2: 33-44.
  3. The Practice of Neuroscience, p. 199-200, John C.M. Brust (2000).

Template:Lesions of spinal cord and brainstem

de:Brown-Séquard-Syndrom


Template:WikiDoc Sources