Breast cancer bone metastasis: Difference between revisions

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==Overview==
==Overview==
Bone is the most common site of breast cancer recurrence <ref name="pmid17062708">{{cite journal| author=Coleman RE| title=Clinical features of metastatic bone disease and risk of skeletal morbidity. | journal=Clin Cancer Res | year= 2006 | volume= 12 | issue= 20 Pt 2 | pages= 6243s-6249s | pmid=17062708 | doi=10.1158/1078-0432.CCR-06-0931 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17062708  }} </ref>, <ref name="pmid3814476">{{cite journal| author=Coleman RE, Rubens RD| title=The clinical course of bone metastases from breast cancer. | journal=Br J Cancer | year= 1987 | volume= 55 | issue= 1 | pages= 61-6 | pmid=3814476 | doi= | pmc=PMC2001575 | url= }} </ref>. A Skeletal-Related event (sre)is defined as any of the following:
Bone is the most common site of breast cancer distant spread. bone metastases due to breast cancer cause major morbidity, decrease survival and reduce quality of life of many patients.
Cancer effects on the skeleton are mainly pain and Skeletal-Related events (sre), defined as any of the following:
*pathologic fracture,  
*pathologic fracture,  
*a requirement for surgical intervention and palliative radiotherapy to bone lesions,
*a requirement for surgical intervention and palliative radiotherapy to bone lesions,
*spinal cord compression
*spinal cord compression
*hypercalcemia of malignancy
*hypercalcemia of malignancy
SRE cause major morbidity, decrease survival and reduce quality of life.


==References==
==References==

Revision as of 14:00, 23 November 2011

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-In-Chief: Jack Khouri

Overview

Bone is the most common site of breast cancer distant spread. bone metastases due to breast cancer cause major morbidity, decrease survival and reduce quality of life of many patients. Cancer effects on the skeleton are mainly pain and Skeletal-Related events (sre), defined as any of the following:

  • pathologic fracture,
  • a requirement for surgical intervention and palliative radiotherapy to bone lesions,
  • spinal cord compression
  • hypercalcemia of malignancy

References

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