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Revision as of 17:57, 30 October 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Most laboratory tests are not diagnostic for brain abscess.

Laboratory Findings

Blood examinations may reveal inflammatory signs with an elevation of C-reactive proteins.[1] Laboratory findings consistent with the diagnosis of brain abscesses include cerebrospinal fluid (CSF) analysis and erythrocyte sedimentation rate (ESR).[2]

  • In approximately 25% of findings, the CSF is normal or shows unspecific changes.
    • It is difficult to isolate the pathogens from the CSF due to a lack of communication of the abscess with the CSF spaces.[1]
  • Some patients have been seen to herniate after CSF procedure.
    • In one study, 41 out of 120 patients deteriorated within 48 hours, and 25 of these individuals died.
  • There is a moderate increase in ESR.[3]

References

  1. 1.0 1.1 Hähnel, Stefan (2009), Inflammatory Diseases of the Brain (2nd ed.), Berlin, Germany: Springer
  2. Schlossberg, David (2008), Clinical Infectious Disease (1st ed.), New York, New York: Cambridge University Press
  3. Schlossberg, David (2008), Clinical Infectious Disease (1st ed.), New York, New York: Cambridge University Press

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