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Bornholm disease is often due to either the [[Coxsackie A virus|Coxsackie virus]] or [[echovirus]]. The most prevalent strains include:
Bornholm disease is often due to either the [[Coxsackie A virus|Coxsackie virus]] or [[echovirus]]. The most prevalent strains include:


* Coxsackievirus B (CBV) and less coxsackievirus A (CAV) types 4, 6, 9 and 10
* Coxsackievirus B (CBV) types B3 and B4
* Coxsackievirus A (CAV) types 4, 6, 9 and 10
* Echovirus types 1, 6, 8, 9 and 19
* Echovirus types 1, 6, 8, 9 and 19


Generally,  Coxsackievirus B virus is more prevalent in regards to respiratory complaints compared to Coxsackievirus A strains.<ref name="pmid303647402">Lal A, Akhtar J, Isaac S, Mishra AK, Khan MS, Noreldin M | display-authors=etal (2018) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=30364740 Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature.] ''Respir Med Case Rep'' 25 ():270-273. [http://dx.doi.org/10.1016/j.rmcr.2018.10.005 DOI:10.1016/j.rmcr.2018.10.005] PMID: [https://pubmed.gov/30364740 30364740]</ref>
Generally,  Coxsackievirus B virus is more prevalent in regards to respiratory complaints compared to Coxsackievirus A strains. Apart from respiratory symptoms, the Coxsackievirus B virus has also presented with cases of aseptic meningitis, pericarditis, and orchitis. <ref name="pmid303647402">Lal A, Akhtar J, Isaac S, Mishra AK, Khan MS, Noreldin M | display-authors=etal (2018) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=30364740 Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature.] ''Respir Med Case Rep'' 25 ():270-273. [http://dx.doi.org/10.1016/j.rmcr.2018.10.005 DOI:10.1016/j.rmcr.2018.10.005] PMID: [https://pubmed.gov/30364740 30364740]</ref> The clinical spectrum varies depending on age groups for the Coxsackievirus A and B strains of the virus. Although severe progression of the disease is rare, it has been associated in particular with the Coxsackievirus B3 virus.<ref name="pmid24504149">{{cite journal| author=Lee CJ, Huang YC, Yang S, Tsao KC, Chen CJ, Hsieh YC | display-authors=etal| title=Clinical features of coxsackievirus A4, B3 and B4 infections in children. | journal=PLoS One | year= 2014 | volume= 9 | issue= 2 | pages= e87391 | pmid=24504149 | doi=10.1371/journal.pone.0087391 | pmc=3913601 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24504149  }} </ref>


==References==
==References==

Revision as of 06:47, 14 February 2022


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz

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Overview

Bornholm disease usually is caused by one of the group B coxsackie viruses and is less often caused by a group A coxsackie virus or an echovirus.

Causes

Bornholm disease is often due to either the Coxsackie virus or echovirus. The most prevalent strains include:

  • Coxsackievirus B (CBV) types B3 and B4
  • Coxsackievirus A (CAV) types 4, 6, 9 and 10
  • Echovirus types 1, 6, 8, 9 and 19

Generally, Coxsackievirus B virus is more prevalent in regards to respiratory complaints compared to Coxsackievirus A strains. Apart from respiratory symptoms, the Coxsackievirus B virus has also presented with cases of aseptic meningitis, pericarditis, and orchitis. [1] The clinical spectrum varies depending on age groups for the Coxsackievirus A and B strains of the virus. Although severe progression of the disease is rare, it has been associated in particular with the Coxsackievirus B3 virus.[2]

References

  1. Lal A, Akhtar J, Isaac S, Mishra AK, Khan MS, Noreldin M | display-authors=etal (2018) Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature. Respir Med Case Rep 25 ():270-273. DOI:10.1016/j.rmcr.2018.10.005 PMID: 30364740
  2. Lee CJ, Huang YC, Yang S, Tsao KC, Chen CJ, Hsieh YC; et al. (2014). "Clinical features of coxsackievirus A4, B3 and B4 infections in children". PLoS One. 9 (2): e87391. doi:10.1371/journal.pone.0087391. PMC 3913601. PMID 24504149.

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