Bladder exstrophy: Difference between revisions

Jump to navigation Jump to search
No edit summary
 
No edit summary
 
(4 intermediate revisions by 3 users not shown)
Line 1: Line 1:
<div style="-webkit-user-select: none;">
{|class="infobox" style="position: fixed; top: 65%; right: 10px; margin: 0 0 0 0; border: 0; float: right;
|-
| {{#ev:youtube|https://https://www.youtube.com/watch?v=gM6mmi8sYSo|350}}
|-
|}
{{Infobox_Disease |
{{Infobox_Disease |
   Name          = Bladder exstrophy |
   Name          = Bladder exstrophy |
Line 9: Line 15:
   OMIM          = 600057 |
   OMIM          = 600057 |
   MedlinePlus    = |
   MedlinePlus    = |
  eMedicineSubj  = ped |
  eMedicineTopic = 704 |
   MeshName      = Bladder+Exstrophy |
   MeshName      = Bladder+Exstrophy |
   MeshNumber    = C12.740.700.132 |
   MeshNumber    = C12.740.700.132 |
Line 17: Line 21:
{{SCC}}
{{SCC}}


{{Editor Help}}
 


==Overview==
==Overview==
Line 38: Line 42:


The spectrum of disease extends from spade penis and [[epispadias]] on one hand, to exstrophy with cloaca (also known as [[cloacal exstrophy]]).
The spectrum of disease extends from spade penis and [[epispadias]] on one hand, to exstrophy with cloaca (also known as [[cloacal exstrophy]]).
==Diagnosis==
<gallery>
Image:
Bladder-exstrophy-001.jpg
Image:
Bladder-exstrophy-002.jpg
Image:
Bladder-exstrophy-003.jpg
</gallery>


==Treatment==
==Treatment==
Line 56: Line 77:


{{Congenital malformations of genital organs and urinary system}}
{{Congenital malformations of genital organs and urinary system}}
{{SIB}}
[[Category:Diseases]]
[[Category:Urology]]
[[Category:Congenital disorders]]


[[de:Blasenekstrophie]]
[[de:Blasenekstrophie]]
Line 67: Line 83:
{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WS}}
{{WS}}
[[Category:Disease]]
[[Category:Urology]]
[[Category:Congenital disorders]]

Latest revision as of 17:04, 7 July 2017

https://https://www.youtube.com/watch?v=gM6mmi8sYSo%7C350}}
Bladder exstrophy
ICD-10 Q64.1
ICD-9 753.5
OMIM 600057
DiseasesDB 33377
MeSH C12.740.700.132

Template:Search infobox Steven C. Campbell, M.D., Ph.D.


Overview

Bladder exstrophy, more properly, the exstrophy-epispadias complex is a rare congenital anomality occurring once every 40,000-50,000 live births with a 2:1 male:female ratio. The diagnosis involves a spectrum of anomalies of the lower abdominal wall, bladder, anterior bony pelvis, and external genitalia. It occurs due to failure of the abdominal wall to close during fetal development and results in protrusion of the posterior bladder wall through the lower abdominal wall.

Treatment is with surgical correction of the defect, but patients can still have long term issues with urinary tract infections and sexual dysfunction.

Pathogenesis

The cause of bladder exstrophy is maldevelopment of the lower abdominal wall, leading to a rupture which causes the bladder to communicate with the amniotic fluid.

Spectrum of anomalies

The typical manifestation of exstrophy-epispadias complex is

  • bladder everted through a midline lower abdominal wall defect
  • widening of the pubic symphysis
  • epispadias in males (dorsal cleft in the penis, exposing the urethral mucosa)
  • bifid clitoris in females, with a short "urethral strip" indistinguishable from bladder mucosa.

The spectrum of disease extends from spade penis and epispadias on one hand, to exstrophy with cloaca (also known as cloacal exstrophy).

Diagnosis

Treatment

Modern therapy is aimed at surgical reconstruction of the bladder and genitalia

Prognosis

Even with successful surgery, patients may have long-term problems with

  • incontinence
  • urinary reflux
  • repeated urinary tract infections
  • sexual dysfunction

External links

de:Blasenekstrophie


Template:WS