Benzoyl peroxide: Difference between revisions

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{{Chembox new|
{{DrugProjectFormSinglePage
ImageFile=Benzoyl-peroxide-2D-skeletal.png|
|authorTag={{Ammu}}
IUPACName=Dibenzoyldioxidane|
|OTC=Yes
Formula=(C<sub>6</sub>H<sub>5</sub>CO)<sub>2</sub>O<sub>2</sub> or C<sub>14</sub>H<sub>10</sub>O<sub>4</sub>|
|genericName=benzoyl peroxide
MolarMass=242.23 g/mol|
|aOrAn=an
CASNo=94-36-0|
|drugClass=[[antiseptic]]
Density=1.334 g/cm<sup>3</sup>|
|indicationType=treatment
MeltingPt=103&ndash;5 °C ''decomp.''|
|indication=[[acne]]
Solubility=Poor|
|adverseReactions=[[hypersensitivity]], [[contact dermatitis]], [[erythema]]
  Solvent=Water|
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
SMILES=c1ccccc1C(=O)OOC(=O)c2ccccc2|
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
Section1={{Chembox Hazards|
  EUClass=Explosive ('''E''')<br/>Irritant ('''Xi''')|
  EUIndex=617-008-00-0|
  NFPA-H=1|
  NFPA-F=4|
  NFPA-R=4|
  NFPA-O=ox|
  RPhrases={{R2}}, {{R36}}, {{R43}}|
  SPhrases={{S2}}, {{S3/7}}, {{S14}}, {{S36/37/39}}|
  Autoignition=80°C|
  RTECS=DM8575000}}}}
{{SI}}
{{EH}}


==Overview==
* Content
[[Image:Benzoyl peroxide gel.jpg|thumb|left|200px|Tube of Basiron, a water-based 5% benzoyl peroxide preparation for the treatment of [[Acne vulgaris|acne]].]]
'''Benzoyl peroxide''' ([[International Phonetic Alphabet|IPA]] {{IPA|[ˈbɛnzəʊɪl pəˈrɒksaɪd]}}) is a [[chemical]] in the [[organic peroxide]] family. It consists of two benzoyl groups ([[benzaldehyde]] with the H of CHO removed) joined by a [[peroxide]] group.


== Uses ==
<!--Adult Indications and Dosage-->
Benzoyl peroxide is a radical [[initiation|initiator]]. Homolytic cleavage of the weak oxygen-oxygen bond forms [[radical (chemistry)|free radicals]] which trigger further reactions.


Jack Breitbart of [[Revlon]] laboratories first discovered Benzoyl peroxide's use for treating acne.  It is typically placed over the affected areas in gel or cream form, in concentrations of 2.5% increasing through the usually effective 5% to up to 10%. Research suggests that 5 and 10% concentrations are not significantly more effective than 2.5% and 2.5% is usually better tolerated.<ref>{{cite journal | last = Mills | first = OH Jr | coauthors = Kligman AM, Pochi P, Comite H | year = 1986 | title = Comparing 2.5%, 5%, and 10% benzoyl peroxide on inflammatory acne vulgaris. | journal = International Journal of Dermatology | volume = 25 | issue = 10 | pages = 664–667 | pmid = 2948929}}</ref><ref>{{cite journal | last = Yong | first = CC | year = 1979 | title = Benzoyl peroxide gel therapy in acne in Singapore. | journal = International Journal of Dermatology | volume = 18 | issue = 6 | pages = 485–488 | pmid = 158569}}</ref> It commonly causes initial dryness and sometimes irritation, although skin tolerance usually occurs after a week or so. A small percentage of people are much more sensitive to it and liable to suffer burning, itching, peeling and possibly swelling<ref>Typical product information leaflets and monographs</ref>. It is sensible to apply the lowest concentration and build up as appropriate. Once tolerance is achieved, increasing the quantity or concentration a second time and gaining tolerance at a higher level usually gives better subsequent acne clearance. Benzoyl peroxide works as a peeling agent, increasing skin turnover and clearing pores, thus reducing the bacterial count there as well as directly as an antibacterial.
<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult=* For the treatment of [[acne]]
|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.


Other common uses for benzoyl peroxide include [[hair dye|dyeing hair]], and as an active ingredient in teeth whitening systems. It is also used in the preparation of [[flour]], and can be used as an [[initiator]] and  [[catalyst]] for [[polyester]] [[thermoset]] resins (as an alternative to the much more hazardous [[methyl ethyl ketone peroxide]]).
<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport=Postoperative [[wound]] [[infection]]; Prophylaxis<ref name="pmid8056888">{{cite journal| author=Bencini PL, Galimberti M, Signorini M| title=Utility of topical benzoyl peroxide for prevention of surgical skin wound infection. | journal=J Dermatol Surg Oncol | year= 1994 | volume= 20 | issue= 8 | pages= 538-40 | pmid=8056888 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8056888  }} </ref>


== Safety ==
Pure benzoyl peroxide is highly flammable, explosive, toxic and a possible tumor promoter and may act as a mutagen<ref>[http://physchem.ox.ac.uk/MSDS/BE/benzoyl_peroxide.html]</ref>, and should be handled with care.


Diluted in an ointment, benzoyl peroxide is used as an acne treatment and the following precautions and claims pertain to this use. Attention should be paid to the safety directions provided when purchased.
<!--Pediatric Indications and Dosage-->


In the [[United States of America|United States]], the typical concentration for benzoyl peroxide is 2.5% to 10% for both [[Prescription drug|prescription]] and [[Over-the-counter drug|over the counter]] use. Benzoyl peroxide, like most peroxides, is a powerful [[bleach|bleaching]] agent. Contact with fabric (including clothing and bed linens) or hair can cause permanent color dampening almost immediately.  
<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed=There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.


Benzoyl peroxide breaks down in contact with skin, producing [[benzoic acid]] and oxygen, neither of which are significantly toxic.<ref>[http://www.chem.unep.ch/irptc/sids/oecdsids/BENZOYLPER.pdf#search=%22%22benzoyl%20peroxide%22%20decomposition%20vivo%22 "Benzoyl Peroxide" section 3.1.1]</ref>
<!--Off-Label Use and Dosage (Pediatric)-->


When applied to skin benzoyl peroxide has been shown to induce cancer, but ''only'' when used at 100% concentrations; it has not been shown to do this at the far lower concentrations used for treating acne, and at lower concentrations benzoyl peroxide has not been found to be mutagenic or carcinogenic.{{Fact|date=February 2007}}
<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.


Benzoyl peroxide removes the top layer of skin, which also decreases the sun protective effect (roughly [[Sunscreen|SPF]] 3). This can cause sunburn and premature aging if sun protection is not worn. If sun protection is used, benzoyl peroxide has effects similar to [[glycolic acid]] peels which are so-called anti-aging treatments.
<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.


== Double Displacement ==
<!--Contraindications-->
Mixing [[sodium peroxide]] with [[benzoyl chloride]] gives benzoyl peroxide and [[sodium chloride]].
|warnings=* For external use only
* Do not use if you have very sensitive skin are sensitive to benzoyl peroxide
* When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
* Avoid unnecessary sun exposure and use a sunscreen
* Avoid contact with the [[eyes]], [[lips]], and [[mouth]]
* Avoid contact with [[hair]] and dyed fabrics, which may be bleached by this product
* Skin irritation may occur, characterized by redness, burning, [[itching]], peeling, or possibly [[swelling]]. Irritation may be reduced by using the product less frequently or in a lower concentration.
* Stop use and ask a doctor if irritation becomes severe.
* Keep out of reach of children
* If swallowed, get medical help or contact a Poison Control Center right away.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=* [[Hypersensitivity]].
* [[Erythema]].
* [[Contact dermatitis]].


== Decomposition ==
The [[half-life]] of benzoyl peroxide is one hour at 92°C. At 131°C, the half-life is one minute. <ref>{{cite paper | author = Hui Li | title = Synthesis, Characterization and Properties of Vinyl Ester Matrix Resins | date = 1998 | url = http://scholar.lib.vt.edu/theses/available/etd-42198-113329/unrestricted/ch2.pdf | format = [[PDF]] | accessdate = 2007-02-17 }}</ref>


== References ==
<!-- See [[Wikipedia:Footnotes]] for instructions. -->
<references />


== External links ==
<!--Drug Interactions-->
*{{ICSC|0225|02}}
|useInPregnancyFDA=* '''Pregnancy Category'''
*{{PGCH|0052}}
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
*[[IARC]] Monograph "[http://www-cie.iarc.fr/htdocs/monographs/vol71/007-benzoylperox.html Benzoyl peroxide.]"
*[http://www.acnecuresecrets.com/Benzoyl_peroxide.html Benzoyl Peroxide as Acne Treatment] Using Benzoyl Peroxide to treat Acne.
*[http://www.chemicalland21.com/arokorhi/specialtychem/finechem/BENZOYL%20PEROXIDE.htm Benzoyl Peroxide]
*[http://www.acne.org/regimen.html Information on Benzoyl Peroxide Application] - Acne.org Daniel Kern's acne treatment regimen


{{E number infobox 920-929}}
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
{{Acne Agents}}
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
{{SIB}}
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.
 
<!--Administration and Monitoring-->
|administration=* Topical
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.
 
<!--Overdosage-->
|drugBox={{chembox2
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 477313648
| ImageFile_Ref = {{chemboximage|correct|??}}
| ImageFile = Benzoyl-peroxide.svg
| ImageName = Skeletal formula
| ImageFile1 = Benzoyl-peroxide-3D-balls.png
| ImageName1 = Ball-and-stick model
| IUPACName = dibenzoyl peroxide
| OtherNames = benzoyl peroxide
|Section1={{Chembox Identifiers
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = W9WZN9A0GM
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1200370
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D03093
| InChI =1/C14H10O4/c15-13(11-7-3-1-4-8-11)17-18-14(16)12-9-5-2-6-10-12/h1-10H
| InChIKey = OMPJBNCRMGITSC-UHFFFAOYAV
| SMILES = c1ccc(cc1)C(=O)OOC(=O)c2ccccc2
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C14H10O4/c15-13(11-7-3-1-4-8-11)17-18-14(16)12-9-5-2-6-10-12/h1-10H
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = OMPJBNCRMGITSC-UHFFFAOYSA-N
| CASNo = 94-36-0
| CASNo_Ref = {{cascite|correct|CAS}}
| EC-number = 202-327-6
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 6919
| PubChem = 7187
| ATCCode_prefix = D10
| ATCCode_suffix = AE01
| ATC_Supplemental = {{ATCvet|D11|AX90}}
| RTECS = DM8575000
  }}
|Section2={{Chembox Properties
| C =14|H=10 |O=4
| Appearance = colourless solid
| Density = 1.334 g/cm<sup>3</sup>
| MeltingPtC = 103 to 105
| Melting_notes = decomposes
| Solubility = poor
  }}
|Section5={{Chembox Pharmacology
| AdminRoutes = topical
| Bioavail =
| Metabolism =
| HalfLife =
| ProteinBound =
| Excretion =
| Legal_status =
| Legal_US = OTC
| Legal_UK =
| Legal_AU =
| Legal_CA =
| PregCat =
| PregCat_AU =
| PregCat_US = C
| Licence_US = Benzoyl+peroxide
  }}
|Section7={{Chembox Hazards
| EUIndex = 617-008-00-0
| EUClass = Explosive ('''E''')<br/>Irritant ('''Xi''')
| RPhrases = {{R3}}, {{R7}}, {{R36}}, {{R43}}
| SPhrases = {{S2}}, {{S3/7}}, {{S14}}, {{S36/37/39}}
| NFPA-H = 3
| NFPA-F = 1
| NFPA-R = 3
| NFPA-O = ox
| AutoignitionPtC = 80
| Autoignition_notes =
  }}
}}
|mechAction=<!--Structure-->
|structure=<!--Pharmacodynamics-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.
 
<!--Pharmacokinetics-->
|PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.
 
<!--Nonclinical Toxicology-->
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.
 
<!--Clinical Studies-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.
 
<!--How Supplied-->
|packLabel=[[File:Benzyl peroxide 01.jpg|thumb|none|400px|This image is provided by the National Library of Medicine.]]
[[File:DailyMed - GLYTONE ACNE- benzoyl peroxide gel  .png|thumb|none|400px|This image is provided by the National Library of Medicine.]]
|fdaPatientInfo=There is limited information regarding <i>Patient Counseling Information</i> of {{PAGENAME}} in the drug label.
 
<!--Precautions with Alcohol-->
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
 
<!--Brand Names-->
|brandNames=*GLYTONE ACNE ®<ref>{{Cite web | title =GLYTONE ACNE- benzoyl peroxide gel  | url= http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=80e8c76c-ad80-41e2-8711-091868970564}}</ref>
 
<!--Look-Alike Drug Names-->
|drugShortage=
}}
<!--Pill Image-->
 
 
 
<!--Label Display Image-->
 
 
 
 
 
<!--Category-->
 
[[Category:Drug]]
[[Category:IARC Group 3 carcinogens]]
[[Category:Organic peroxides]]
[[Category:Organic peroxides]]
[[Category:Dermatological preparations]]
[[Category:IARC Group 3 carcinogens]]
[[de:Dibenzoylperoxid]]
[[fr:Peroxyde de benzoyle]]
[[nl:Benzoylperoxide]]
[[pt:Peróxido de benzoíla]]
[[ja:過酸化ベンゾイル]]
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}

Latest revision as of 14:32, 10 March 2015

Benzoyl peroxide
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.
NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Overview

Benzoyl peroxide is an antiseptic that is FDA approved for the treatment of acne. Common adverse reactions include hypersensitivity, contact dermatitis, erythema.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

  • For the treatment of acne

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Benzoyl peroxide in adult patients.

Non–Guideline-Supported Use

Postoperative wound infection; Prophylaxis[1]

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding FDA-Labeled Use of Benzoyl peroxide in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Benzoyl peroxide in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Benzoyl peroxide in pediatric patients.

Contraindications

There is limited information regarding Benzoyl peroxide Contraindications in the drug label.

Warnings

  • For external use only
  • Do not use if you have very sensitive skin are sensitive to benzoyl peroxide
  • When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
  • Avoid unnecessary sun exposure and use a sunscreen
  • Avoid contact with the eyes, lips, and mouth
  • Avoid contact with hair and dyed fabrics, which may be bleached by this product
  • Skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.
  • Stop use and ask a doctor if irritation becomes severe.
  • Keep out of reach of children
  • If swallowed, get medical help or contact a Poison Control Center right away.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Benzoyl peroxide in the drug label.

Postmarketing Experience

Drug Interactions

There is limited information regarding Benzoyl peroxide Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Benzoyl peroxide in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Benzoyl peroxide during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Benzoyl peroxide with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Benzoyl peroxide with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Benzoyl peroxide with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Benzoyl peroxide with respect to specific gender populations.

Race

There is no FDA guidance on the use of Benzoyl peroxide with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Benzoyl peroxide in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Benzoyl peroxide in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Benzoyl peroxide in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Benzoyl peroxide in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Topical

Monitoring

There is limited information regarding Monitoring of Benzoyl peroxide in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Benzoyl peroxide in the drug label.

Overdosage

There is limited information regarding Benzoyl peroxide overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

Template:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox E numberTemplate:Chembox RTECSTemplate:Chembox AppearanceTemplate:Chembox DensityTemplate:Chembox MeltingPtTemplate:Chembox SolubilityInWaterTemplate:Chembox PharmacologyTemplate:Chembox EUClassTemplate:Chembox RPhrasesTemplate:Chembox SPhrasesTemplate:Chembox NFPATemplate:Chembox AutoignitionPtTemplate:Chembox Supplement
Template:Chembox header2 | Benzoyl peroxide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
KEGG
UNII
Properties
C14H10O4
Molar mass 242.23 g·mol−1
Hazards
Template:Chembox header2 | Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Mechanism of Action

There is limited information regarding Benzoyl peroxide Mechanism of Action in the drug label.

Structure

There is limited information regarding Benzoyl peroxide Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Benzoyl peroxide in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Benzoyl peroxide in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Benzoyl peroxide in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Benzoyl peroxide in the drug label.

How Supplied

There is limited information regarding Benzoyl peroxide How Supplied in the drug label.

Storage

There is limited information regarding Benzoyl peroxide Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Benzoyl peroxide |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

This image is provided by the National Library of Medicine.
This image is provided by the National Library of Medicine.

{{#ask: Label Page::Benzoyl peroxide |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Benzoyl peroxide in the drug label.

Precautions with Alcohol

  • Alcohol-Benzoyl peroxide interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

  • GLYTONE ACNE ®[2]

Look-Alike Drug Names

There is limited information regarding Benzoyl peroxide Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. Bencini PL, Galimberti M, Signorini M (1994). "Utility of topical benzoyl peroxide for prevention of surgical skin wound infection". J Dermatol Surg Oncol. 20 (8): 538–40. PMID 8056888.
  2. "GLYTONE ACNE- benzoyl peroxide gel".