Benzethonium chloride

Benzethonium chloride

Clinical data
Routes of administration	Topical
ATC code	D08AJ58 (WHO)
Legal status
Legal status	US: OTC
Identifiers
IUPAC name benzyl-dimethyl-[2-[2-[4- (2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl] azanium chloride
CAS Number	121-54-0
PubChem CID	8478
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C27H42ClNO2
Molar mass	448.081 g/mol
3D model (JSmol)	Interactive image
SMILES C[N+](CCO CCOc2ccc (C(C)(C)CC(C)(C)C) cc2)(C)Cc1 ccccc1[Cl-]

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Benzethonium chloride is a synthetic quaternary ammonium, surfactant, antiseptic, and anti-infective compound used as a topical antimicrobial agent in cosmetics and personal care products like anti-itch ointments and antibacterial moist towelettes and wipes. Benzothonium chloride is also used is the food industry as a disinfectant and preservative. [3]. It has the appearance of an odorless white crystalline hygroscopic powder and has a melting point of 162-164 °C. The compound is moderately soluble in water and is toxic orally because it may cause failure in neuromuscular transmission as a result of pathological disturbance at the myoneural junction.[4]

It is available under trade names salanine, BZT, diapp, quatrachlor, polymine d, phemithyn, antiseptol, disilyn, phermerol, and others. [5]

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