Behçet's disease epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]

Overview

Epidemiology and Demographics

Prevalence

  • The prevalence of behcet disease is approximately 80 to 370 per 100,000 individuals in Turkey[1][2]
  • The prevalence of behcet disease is approximately 13.5 to 20 per 100,000 individuals in Iran, Japan, Korea, China and Saudi Arabia[1]
  • The prevalence of behcet disease is approximately 7.1 per 100,000 individuals in Paris, France[3]
  •  The prevalence of behcet disease is approximately 2.4 per 100,000 individuals in European ancestry[3]
  •  The prevalence of behcet disease is approximately 34.6 per 100,000 individuals in North African ancestry[3]
  • The prevalence of behcet disease is approximately 17.5 per 100,000 individuals in Asian ancestry[3]
  • The prevalence of behcet disease is approximately 0.12 to 7.5 per 100,000 individuals in the United States[4]

Age

  • Behcet disease commonly affects young adults 20 to 40 years of age[5]

Race

  • Behcet disease usually affects individuals of the Turkish, Asian, and Middle Eastern populations.
  • Middle Eastern and Asian individuals are more likely to develop Behcet disease due to the increased incidence of skin pathergy and HLA-B51 antigen

Gender

  • Males are more commonly affected by Behcet disease than females. The male to female ratio ranges from approximately 11 to 1 to 2 to 1

Region

  • The majority of behcet disease cases are reported along the ancient silk road ( from eastern Asia to the Mediterranean)[1]
  • Behcet disease is most common in Turkey

References

  1. 1.0 1.1 1.2 Sakane T, Takeno M, Suzuki N, Inaba G (October 1999). "Behçet's disease". N. Engl. J. Med. 341 (17): 1284–91. doi:10.1056/NEJM199910213411707. PMID 10528040.
  2. Sarica-Kucukoglu R, Akdag-Kose A, KayabalI M, Yazganoglu KD, Disci R, Erzengin D; et al. (2006). "Vascular involvement in Behçet's disease: a retrospective analysis of 2319 cases". Int J Dermatol. 45 (8): 919–21. doi:10.1111/j.1365-4632.2006.02832.x. PMID 16911374.
  3. 3.0 3.1 3.2 3.3 Mahr A, Belarbi L, Wechsler B, Jeanneret D, Dhote R, Fain O, Lhote F, Ramanoelina J, Coste J, Guillevin L (December 2008). "Population-based prevalence study of Behçet's disease: differences by ethnic origin and low variation by age at immigration". Arthritis Rheum. 58 (12): 3951–9. doi:10.1002/art.24149. PMID 19035493.
  4. Calamia KT, Wilson FC, Icen M, Crowson CS, Gabriel SE, Kremers HM (May 2009). "Epidemiology and clinical characteristics of Behçet's disease in the US: a population-based study". Arthritis Rheum. 61 (5): 600–4. doi:10.1002/art.24423. PMC 3024036. PMID 19405011.
  5. Sakane T, Takeno M, Suzuki N, Inaba G (October 1999). "Behçet's disease". N. Engl. J. Med. 341 (17): 1284–91. doi:10.1056/NEJM199910213411707. PMID 10528040.

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