Behçet's disease (patient information)

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What is Behçet's disease?

How do I know if I have Behçet's disease and what are the symptoms of Behçet's disease?

Signs and symptoms of Behcet's disease vary from person to person, depending on the blood vessels affected. Many patients show multiple damages. Like other autoimmue diseases, signs and symptoms come and go.

Painful mouth sores: These are the most common sign of Behcet's disease. Mouth sores turn quickly from lesion to ulcers and heal in 7~21 days.
Skin lesions: Skin lesions in patients with Behçet's disease vary, from acne-like sores to red tender nodules.
Brain: When Behcet's disease affect brain, it leads to headache, fever, disorientation, poor balance, even stroke.
Digestive system: Patients with Behcet's disease may show symptoms such as abdominal pain, diarrhea or bleeding.
Eyes: Behcet's disease may cause inflammation in the eye, such as uveitis.
Joints: Patients with Behçet's disease may have joint swelling and joint painwhen joints are affected with inflammination.
Vascular system: Inflammination may occur on veins and large arteries, leading redness, pain and swelling in the arms or legs, even aneurysms and narrowing or blockage of the vessel.
Genitals: Patients with Behcet's disease may develop sores on their genitals, feeling pain and leaving scars.

Who is at risk for Behçet's disease?

The underlying cause of Behçet’s disease is not clear. It is suggested that the following factors may be associated with the disease.

Genetic predisposition: Researches demonstrate that the presence of the gene HLA–B51 is a risk factor for Behçet's disease.
Age: Behçet's disease can affect people in any age, but the most common age is 20~30 years old.
Gender: Behcet's disease most commonly affects men than women.
Race: Behçet's disease is more common in Middle East and Japan then in other race. It is rare in America.