Basedow syndrome

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Karl Adolph von Basedow was the first doctor to describe Basedow Syndrome, which is characterized by a triad of hyperthyroidism, Goitre, and exophthalmos (bulging eyeballs).


Symptoms include:

cardiac arrhythmias
increased pulse rate
weight loss in the presence of increased appetite
intolerance to heat
elevated basal metabolism rate
profuse sweating
elevated protein-bound iodine level
eyelid retraction and stare.


It is unknown, but it may be related to an autoimmune malfunction or disease. The ratio of onset is 4:1 in females. It is normally discovered in the third or fourth decade of life.