Bambuterol: Difference between revisions

Bambuterol
Clinical data
Pregnancy; category	Unknown;
Routes of; administration	Oral
ATC code	R03CC12 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	20%
Metabolism	Hepatic, extensive; Further metabolized to terbutaline by plasma cholinesterase
Elimination half-life	13 hours (bambuterol); 21 hours (terbutaline)
Excretion	Renal
Identifiers
	IUPAC name {3-(dimethylcarbamoyloxy)-5-[1-hydroxy-2-(tert-butylamino); ethyl]phenyl} N,N-dimethylcarbamate;
CAS Number	81732-46-9;
PubChem CID	54766;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C18H29N3O5
Molar mass	367.44 g/mol

Revision as of 22:44, 8 August 2012

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Bambuterol (INN, marketed by AstraZeneca under the trade names Bambec and Oxeol) is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.

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Clinical data

Pregnancy category	Unknown
Routes of administration	Oral
ATC code	R03CC12 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	20%
Metabolism	Hepatic, extensive Further metabolized to terbutaline by plasma cholinesterase
Elimination half-life	13 hours (bambuterol) 21 hours (terbutaline)
Excretion	Renal
Identifiers
IUPAC name {3-(dimethylcarbamoyloxy)-5-[1-hydroxy-2-(tert-butylamino) ethyl]phenyl} N,N-dimethylcarbamate
CAS Number	81732-46-9
PubChem CID	54766
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₈H₂₉N₃O₅
Molar mass	367.44 g/mol