Babesiosis natural history, complications and prognosis: Difference between revisions

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====Further development if left untreated====
====Further development if left untreated====
*Heightened levels of Parasitemia in blood.
*Heightened levels of parasitemia in blood.
*Severe anemia, hemolysis, thrombocytopenia, leukopenia, and eventually death.
*Severe anemia, hemolysis, thrombocytopenia, leukopenia, and eventually death.



Revision as of 13:40, 18 January 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ilan Dock, B.S.

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Natural History

Progression of a babesiosis infection may present itself in a variety of clinical manifestations, which is potentially a reflection of blood parasitemia levels in the blood.

Asymptomatic

Early Stage

  • Chronic infection within asymptomatic populations remain within the incubation stage.

Late Stage

  • There are no further clinical manifestations

Further development if left untreated

  • Clinical manifestations may occur as an asymptomatic patient becomes immuno-compromised or naturally ages.

Symptomatic

Early Stage

  • Incubation period of 1-6 weeks, however may incubate as long as 3 months.
  • Clinical manifestations will present themselves as non-specific flu like symptoms.
  • Common symptoms will include fever, headache, muscle aches, and pain.
  • Severe illness may occur in older and immuno compromised populations. Severe illness will present itself as malaria-like.
  • Symptoms associated with a severe infection include nausea, emesis, night sweats, and anorexia.

Late Stage

  • Severe hemolysis may lead to jaundice.
  • Other complications include a Shock-like state, renal failure, and pulmonary edema.

Further development if left untreated

  • Heightened levels of parasitemia in blood.
  • Severe anemia, hemolysis, thrombocytopenia, leukopenia, and eventually death.

Complications

Babesiosis can be a very severe illness with complications including:[1]

  • Jaundice
  • Hemoglobinuria

References

  1. Babesiosis Disease. For Health Professionals. Center for Disease Control and Prevention(2015). http://www.cdc.gov/parasites/babesiosis/disease.htmlAccessed December 8, 2015.