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==[[Babesiosis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==[[Babesiosis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
Babesiosis causes a disease very similar to Malaria.  In mild cases, people may experience mild fevers and anemia.  In more severe cases, fevers go up to 105 degrees with shaking chills, and anemia (hemolytic anemia) can become severe.  Organ failure may follow including adult respiratory distress syndrome.


==Diagnosis==
==Diagnosis==

Revision as of 14:03, 10 December 2015

For patient information click here Template:DiseaseDisorder infobox

Babesiosis Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Babesiosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Treatment

Medical Therapy

Prevention

Case Studies

Case #1

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Synonyms and keywords: Babesia microti

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Babesiosis is caused by apicomplexan parasitic organism within the genus Babesia. B. Microti and B. divergens are the two species of Babesia that have been frequently reported as parasitic within human populations.

Historical Perspective

Pathophysiology

Causes

Differentiating Babesiosis from other Diseases

Epidemiology and Demographics

Risk Factors

The most potent risk factors in the development of Babesiosis are a combined effort between environment and season. Babesia parasites are transmitted via tick bites in tick-populated areas. Transmission occurs more frequently during the spring and summer in correlation with heightened periods of tick activity. Other risk factors include repeated exposure to the following potential I. scapularis and Ixodes rodent hosts; white-footed deer mice, rats, voles, chipmunks, and field mice; As well as blood transfusions from donors living within endemic areas.

Natural History, Complications and Prognosis

Babesiosis causes a disease very similar to Malaria. In mild cases, people may experience mild fevers and anemia. In more severe cases, fevers go up to 105 degrees with shaking chills, and anemia (hemolytic anemia) can become severe. Organ failure may follow including adult respiratory distress syndrome.

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Imaging Findings | Other Diagnostic Studies

A wide range of physical findings may be associated with patients suffering from babesiosis. Asymptomatic patients will generally appear healthy without any external signs of infection. However physical examination findings are variable depending on the severity of the infection as well as the patient’s medical history. For patients exhibiting symptoms apparent during physical examination, the most common physical findings may range from a moderate fever and minor display of flu-like symptoms to Hepatomegaly, Petechiae, Ecchymoses and Acute respiratory distress syndrome (ARDS).

Treatment

Medical Therapy | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

The mainstay of therapy for babesiosis is antimicrobial therapy. Patients with mild or moderate disease are treated with a combination of Atovaquone and Azithromycin. Patients with severe disease are treated with either Clindamycin or Clindamycin and Quinine. In life-threatening cases, exchange transfusion is performed.

Case Studies

Case #1

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