BACH2

BTB and CNC homology 1, basic leucine zipper transcription factor 2
Identifiers
Symbols	BACH2 ;
External IDs	Template:OMIM5 HomoloGene: 7240
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

BTB and CNC homology 1, basic leucine zipper transcription factor 2, also known as BACH2, is a human gene.

Further reading

• Oyake T, Itoh K, Motohashi H; et al. (1996). "Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site". Mol. Cell. Biol. 16 (11): 6083–95. PMID 8887638.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kobayashi A, Yamagiwa H, Hoshino H; et al. (2000). "A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain". Mol. Cell. Biol. 20 (5): 1733–46. PMID 10669750.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hoshino H, Kobayashi A, Yoshida M; et al. (2000). "Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element". J. Biol. Chem. 275 (20): 15370–6. PMID 10809773.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sasaki S, Ito E, Toki T; et al. (2000). "Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15". Oncogene. 19 (33): 3739–49. doi:10.1038/sj.onc.1203716. PMID 10949928.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vieira SA, Deininger MW, Sorour A; et al. (2002). "Transcription factor BACH2 is transcriptionally regulated by the BCR/ABL oncogene". Genes Chromosomes Cancer. 32 (4): 353–63. PMID 11746976.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Muto A, Tashiro S, Tsuchiya H; et al. (2002). "Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with promyelocytic leukemia nuclear bodies". J. Biol. Chem. 277 (23): 20724–33. doi:10.1074/jbc.M112003200. PMID 11923289.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kamio T, Toki T, Kanezaki R; et al. (2004). "B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs". Blood. 102 (9): 3317–22. doi:10.1182/blood-2002-12-3656. PMID 12829606.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takakuwa T, Luo WJ, Ham MF; et al. (2004). "Integration of Epstein-Barr virus into chromosome 6q15 of Burkitt lymphoma cell line (Raji) induces loss of BACH2 expression". Am. J. Pathol. 164 (3): 967–74. PMID 14982850.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tashiro S, Muto A, Tanimoto K; et al. (2004). "Repression of PML nuclear body-associated transcription by oxidative stress-activated Bach2". Mol. Cell. Biol. 24 (8): 3473–84. PMID 15060166.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Motamed-Khorasani A, Jurisica I, Letarte M; et al. (2007). "Differentially androgen-modulated genes in ovarian epithelial cells from BRCA mutation carriers and control patients predict ovarian cancer survival and disease progression". Oncogene. 26 (2): 198–214. doi:10.1038/sj.onc.1209773. PMID 16832351.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yoshida C, Yoshida F, Sears DE; et al. (2007). "Bcr-Abl signaling through the PI-3/S6 kinase pathway inhibits nuclear translocation of the transcription factor Bach2, which represses the antiapoptotic factor heme oxygenase-1". Blood. 109 (3): 1211–9. doi:10.1182/blood-2005-12-040972. PMID 17018862.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ono A, Kono K, Ikebe D; et al. (2007). "Nuclear positioning of the BACH2 gene in BCR-ABL positive leukemic cells". Genes Chromosomes Cancer. 46 (1): 67–74. doi:10.1002/gcc.20390. PMID 17044046.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ikeda T, Shibata J, Yoshimura K; et al. (2007). "Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy". J. Infect. Dis. 195 (5): 716–25. doi:10.1086/510915. PMID 17262715.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hoshino H, Nishino TG, Tashiro S; et al. (2007). "Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression". J. Biochem. 141 (5): 719–27. doi:10.1093/jb/mvm073. PMID 17383980.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• BACH2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.