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{{B-cell lymphoma}}
{{B-cell lymphoma}}
{{CMG}} ; {{AE}} {{Adnan Ezici}}
{{CMG}} ; {{AE}} {{Adnan Ezici}}
==Overview==
==Overview==
The following physical examination findings may be present among patients with Hodgkin's lymphoma: [[fever]], [[pruritus]], [[petechiae]], [[jaundice]], [[Lymphadenopathy|peripheral lymphadenopathy]], [[Lymphadenopathy|central lymphadenopathy]], [[wheezing]] , chest tenderness, [[abdominal tenderness]], [[hepatomegaly]], [[splenomegaly]] and [[Lymphadenopathy|peripheral lymphadenopathy]].<ref name="pmid32644754">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=32644754 | doi= | pmc= | url= }} </ref><ref name="pmid29763144">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=29763144 | doi= | pmc= | url= }} </ref><ref name="pmid19999217">{{cite journal| author=Hingorjo MR, Syed S| title=Presentation, staging and diagnosis of lymphoma: a clinical perspective. | journal=J Ayub Med Coll Abbottabad | year= 2008 | volume= 20 | issue= 4 | pages= 100-3 | pmid=19999217 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19999217  }} </ref><ref name="pmid28153383">{{cite journal| author=Armitage JO, Gascoyne RD, Lunning MA, Cavalli F| title=Non-Hodgkin lymphoma. | journal=Lancet | year= 2017 | volume= 390 | issue= 10091 | pages= 298-310 | pmid=28153383 | doi=10.1016/S0140-6736(16)32407-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28153383  }} </ref><ref name="pmid32703953">{{cite journal| author=Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH | display-authors=etal| title=Hodgkin lymphoma. | journal=Nat Rev Dis Primers | year= 2020 | volume= 6 | issue= 1 | pages= 61 | pmid=32703953 | doi=10.1038/s41572-020-0189-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32703953  }} </ref>
The following physical examination findings may be present among patients with Hodgkin's lymphoma: [[fever]], [[pruritus]], [[petechiae]], [[jaundice]], [[Lymphadenopathy|peripheral lymphadenopathy]], [[Lymphadenopathy|central lymphadenopathy]], [[wheezing]] , chest tenderness, [[abdominal tenderness]], [[hepatomegaly]], [[splenomegaly]] and [[Lymphadenopathy|peripheral lymphadenopathy]].
 
==Physical Examination==
The following physical examination findings may be present among patients with B cell lymphomas:<ref name="pmid32644754">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=32644754 | doi= | pmc= | url= }} </ref><ref name="pmid29763144">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume=  | issue=  | pages=  | pmid=29763144 | doi= | pmc= | url= }} </ref><ref name="pmid19999217">{{cite journal| author=Hingorjo MR, Syed S| title=Presentation, staging and diagnosis of lymphoma: a clinical perspective. | journal=J Ayub Med Coll Abbottabad | year= 2008 | volume= 20 | issue= 4 | pages= 100-3 | pmid=19999217 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19999217  }} </ref><ref name="pmid28153383">{{cite journal| author=Armitage JO, Gascoyne RD, Lunning MA, Cavalli F| title=Non-Hodgkin lymphoma. | journal=Lancet | year= 2017 | volume= 390 | issue= 10091 | pages= 298-310 | pmid=28153383 | doi=10.1016/S0140-6736(16)32407-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28153383  }} </ref><ref name="pmid32703953">{{cite journal| author=Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH | display-authors=etal| title=Hodgkin lymphoma. | journal=Nat Rev Dis Primers | year= 2020 | volume= 6 | issue= 1 | pages= 61 | pmid=32703953 | doi=10.1038/s41572-020-0189-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32703953  }} </ref>


===Appearance of the Patient===
===Appearance of the Patient===
*Appearance of the Patients with B cell lymphomas depends on the stage of disease. Patients usually appear [[cachexic|cachectic]].
*Appearance of the Patients with B cell lymphomas depends on the stage of disease. Patients may present with [[cachexic|cachexia]] in late disease stage.
 
===Vital Signs===
*Fever
*[[Tachypnea]]
*Asymmetric pulse
 
===Skin===
*Skin examination of patients with B cell lymphomas include:
**[[Pallor]]
**[[Pruritus]]
**[[Petechiae]]
**[[Jaundice]]
 
===HEENT===
* Abnormalities of the head/hair may include:
**Icteric sclera
**[[Nystagmus]]
*Patients may develop superior vena cava syndrome, which may present with:
**Swelling of the face
**Facial flushing/redness face or cheeks
**Facial tenderness
**Drooping eyelid
**Swelling around the eye
 
===Neck===
*[[Lymphadenopathy|Cervical lymphadenopathy]]
 
===Lungs===
*Thoracic masses suggestive of [[Lymphadenopathy|central lymphadenopathy]]
*Chest tenderness
*Pleural effusion may develop, which has signs and symptoms such as:
**[[Wheezing]]
**Decreased breath sounds
**Asymmetric chest expansion
**Hyperresonance lungs on chest auscultation
 
===Heart===
*Cardiovascular examination of patients with B cell lymphomas is usually normal.
 
===Abdomen===
*Abdominal examination of patients with B cell lymphomas include:
**[[Abdominal distension]]
**[[Abdominal tenderness]]
**[[Hepatosplenomegaly]]
**[[Abdominal mass]]es suggestive of [[Lymphadenopathy|central lymphadenopathy]]
 
===Back===
*Back examination of patients with B cell lymphomas is usually normal.
 
===Genitourinary===
*Genitourinary examination of patients with B cell lymphomas is usually normal.
 
===Neuromuscular===
*Neuromuscular examination of patients with B cell lymphomas is usually normal.
 
===Extremities===
*[[Lymphadenopathy|Peripheral lymphadenopathy]]
*Joint pain
*[[Edema]]
*[[Bone fractures]]


===CNS===
*[[Seizures]]


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Needs content]]


[[Category:Disease]]
[[Category:Disease]]

Revision as of 14:21, 29 June 2022

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]

Overview

The following physical examination findings may be present among patients with Hodgkin's lymphoma: fever, pruritus, petechiae, jaundice, peripheral lymphadenopathy, central lymphadenopathy, wheezing , chest tenderness, abdominal tenderness, hepatomegaly, splenomegaly and peripheral lymphadenopathy.

Physical Examination

The following physical examination findings may be present among patients with B cell lymphomas:[1][2][3][4][5]

Appearance of the Patient

  • Appearance of the Patients with B cell lymphomas depends on the stage of disease. Patients may present with cachexia in late disease stage.

Vital Signs

Skin

HEENT

  • Abnormalities of the head/hair may include:
  • Patients may develop superior vena cava syndrome, which may present with:
    • Swelling of the face
    • Facial flushing/redness face or cheeks
    • Facial tenderness
    • Drooping eyelid
    • Swelling around the eye

Neck

Lungs

  • Thoracic masses suggestive of central lymphadenopathy
  • Chest tenderness
  • Pleural effusion may develop, which has signs and symptoms such as:
    • Wheezing
    • Decreased breath sounds
    • Asymmetric chest expansion
    • Hyperresonance lungs on chest auscultation

Heart

  • Cardiovascular examination of patients with B cell lymphomas is usually normal.

Abdomen

Back

  • Back examination of patients with B cell lymphomas is usually normal.

Genitourinary

  • Genitourinary examination of patients with B cell lymphomas is usually normal.

Neuromuscular

  • Neuromuscular examination of patients with B cell lymphomas is usually normal.

Extremities

CNS

References

  1. ↑ "StatPearls". 2022. PMID 32644754 Check |pmid= value (help).
  2. ↑ "StatPearls". 2022. PMID 29763144.
  3. ↑ Hingorjo MR, Syed S (2008). "Presentation, staging and diagnosis of lymphoma: a clinical perspective". J Ayub Med Coll Abbottabad. 20 (4): 100–3. PMID 19999217.
  4. ↑ Armitage JO, Gascoyne RD, Lunning MA, Cavalli F (2017). "Non-Hodgkin lymphoma". Lancet. 390 (10091): 298–310. doi:10.1016/S0140-6736(16)32407-2. PMID 28153383.
  5. ↑ Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH; et al. (2020). "Hodgkin lymphoma". Nat Rev Dis Primers. 6 (1): 61. doi:10.1038/s41572-020-0189-6. PMID 32703953 Check |pmid= value (help).


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