Astrocytoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Epidemiology and Demographics
- Pilocytic astrocytoma accounting for between 0.6-5.1% of all intracranial neoplasms (1.7-7% of all glial tumours) are the most common primary brain tumour of childhood, accounting for 70-85% of all cerebellar astrocytomas.[1]
Prevalence
- In 2012, there were an estimated 148,818 people living with brain and other nervous system cancer in the United States.
Incidence
- The number of new cases of brain and other nervous system cancer was 6.4 per 100,000 men and women per year.
- The number of deaths was 4.3 per 100,000 men and women per year. These rates are age-adjusted and based on 2008-2012 cases and deaths.
- The rates for new brain and other nervous system cancer cases have been falling on average 0.2% each year over the last 10 years
Age
- People can develop astrocytomas at any age.
- The low-grade type is more often found in children or young adults, while the high-grade type are more prevalent in adults.
- Astrocytomas in the base of the brain are more common in young people and account for roughly 75% of neuroepithelial tumors.
- Subependymal giant cell tumours are a well known manifestation of TS, affecting 5-15% of patients with the condition. They are principally diagnosed in patients under 20 years of age, but are occasionally found in older people[2].
- Anaplastic astrocytomas occur in adulthood with peak incidence between 40 and 50 years of age, which is older than low grade astrocytomas and younger than glioblastoma.[3]
- Pilocytic astrocytomas are tumours of young people, with 75% occurring in the first two decades of life, typically late in the first decade (9-10 years). There is no recognised gender predisposition.[2]
Mortality
- The number of deaths was 4.3 per 100,000 men and women per year based on 2008-2012 deaths.
References
- ↑ "Surveillance, Epidemiology, and End Results Program".
- ↑ 2.0 2.1 "Subependymal giant cell astrocytoma [Dr Bruno Di Muzio and Dr Jeremy Jones]".
- ↑ Atlas, Scott (2009). Magnetic resonance imaging of the brain and spine. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. ISBN 078176985X.