Aortic stenosis prevention: Difference between revisions
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| [[File:Siren.gif|30px|link=Aortic stenosis resident survival guide]]|| <br> || <br> | |||
| [[Aortic stenosis resident survival guide|'''Resident'''<br>'''Survival'''<br>'''Guide''']] | |||
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{{Aortic stenosis}} | {{Aortic stenosis}} | ||
{{CMG}}; '''Associate Editor-In-Chief:''' [[User:Mohammed Sbeih|Mohammed A. Sbeih, M.D.]] [mailto:msbeih@wikidoc.org]; {{USAMA}} | |||
==Overview== | ==Overview== | ||
The risk of developing aortic stenosis following [[rheumatic heart disease]] can be minimized with early [[antibiotic]] therapy among patients with documented [[streptococcal pharyngitis]] ([[strep throat]]).<ref name="pmid7567345">{{cite journal| author=Dajani A, Taubert K, Ferrieri P, Peter G, Shulman S| title=Treatment of acute streptococcal pharyngitis and prevention of rheumatic fever: a statement for health professionals. Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, the American Heart Association. | journal=Pediatrics | year= 1995 | volume= 96 | issue= 4 Pt 1 | pages= 758-64 | pmid=7567345 | doi= | pmc= | url= }} </ref> [[Bicuspid aortic valve]] disease is a congenital variant and cannot be prevented. As for calcific aortic stenosis, a number of small, [[observational studies]] have demonstrated an association between lowering cholesterol levels and decreasing the progression of the aortic stenosis;<ref>{{cite journal |author=Moura LM, Ramos SF, Zamorano JL, ''et al'' |title=Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis |journal=J. Am. Coll. Cardiol. |volume=49 |issue=5 |pages=554-61 |year=2007 |pmid=17276178 |doi=10.1016/j.jacc.2006.07.072}}</ref> however, randomized clinical trials have failed to corroborate these findings.<ref name="pmid18765433">{{cite journal| author=Rossebø AB, Pedersen TR, Boman K, Brudi P, Chambers JB, Egstrup K et al.| title=Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis. | journal=N Engl J Med | year= 2008 | volume= 359 | issue= 13 | pages= 1343-56 | pmid=18765433 | doi=10.1056/NEJMoa0804602 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18765433 }} </ref><ref name="pmid15944423">{{cite journal| author=Cowell SJ, Newby DE, Prescott RJ, Bloomfield P, Reid J, Northridge DB et al.| title=A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis. | journal=N Engl J Med | year= 2005 | volume= 352 | issue= 23 | pages= 2389-97 | pmid=15944423 | doi=10.1056/NEJMoa043876 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15944423 }} </ref><ref name="pmid20048204">{{cite journal| author=Chan KL, Teo K, Dumesnil JG, Ni A, Tam J, ASTRONOMER Investigators| title=Effect of Lipid lowering with rosuvastatin on progression of aortic stenosis: results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trial. | journal=Circulation | year= 2010 | volume= 121 | issue= 2 | pages= 306-14 | pmid=20048204 | doi=10.1161/CIRCULATIONAHA.109.900027 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20048204 }} </ref> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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{{WikiDoc Sources}} | |||
[[CME Category::Cardiology]] | |||
[[Category:Disease]] | |||
[[Category:Valvular heart disease]] | [[Category:Valvular heart disease]] | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Congenital heart disease]] | |||
[[Category:Cardiac surgery]] | [[Category:Cardiac surgery]] | ||
[[Category:Surgery]] | [[Category:Surgery]] | ||
Latest revision as of 16:12, 5 January 2017
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Resident Survival Guide |
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Aortic Stenosis Microchapters |
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Diagnosis |
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Treatment |
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Percutaneous Aortic Balloon Valvotomy (PABV) or Aortic Valvuloplasty |
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Transcatheter Aortic Valve Replacement (TAVR) |
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Case Studies |
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Aortic stenosis prevention On the Web |
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American Roentgen Ray Society Images of Aortic stenosis prevention |
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Risk calculators and risk factors for Aortic stenosis prevention |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Mohammed A. Sbeih, M.D. [2]; Usama Talib, BSc, MD [3]
Overview
The risk of developing aortic stenosis following rheumatic heart disease can be minimized with early antibiotic therapy among patients with documented streptococcal pharyngitis (strep throat).[1] Bicuspid aortic valve disease is a congenital variant and cannot be prevented. As for calcific aortic stenosis, a number of small, observational studies have demonstrated an association between lowering cholesterol levels and decreasing the progression of the aortic stenosis;[2] however, randomized clinical trials have failed to corroborate these findings.[3][4][5]
References
- ↑ Dajani A, Taubert K, Ferrieri P, Peter G, Shulman S (1995). "Treatment of acute streptococcal pharyngitis and prevention of rheumatic fever: a statement for health professionals. Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, the American Heart Association". Pediatrics. 96 (4 Pt 1): 758–64. PMID 7567345.
- ↑ Moura LM, Ramos SF, Zamorano JL; et al. (2007). "Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis". J. Am. Coll. Cardiol. 49 (5): 554–61. doi:10.1016/j.jacc.2006.07.072. PMID 17276178.
- ↑ Rossebø AB, Pedersen TR, Boman K, Brudi P, Chambers JB, Egstrup K; et al. (2008). "Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis". N Engl J Med. 359 (13): 1343–56. doi:10.1056/NEJMoa0804602. PMID 18765433.
- ↑ Cowell SJ, Newby DE, Prescott RJ, Bloomfield P, Reid J, Northridge DB; et al. (2005). "A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis". N Engl J Med. 352 (23): 2389–97. doi:10.1056/NEJMoa043876. PMID 15944423.
- ↑ Chan KL, Teo K, Dumesnil JG, Ni A, Tam J, ASTRONOMER Investigators (2010). "Effect of Lipid lowering with rosuvastatin on progression of aortic stenosis: results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trial". Circulation. 121 (2): 306–14. doi:10.1161/CIRCULATIONAHA.109.900027. PMID 20048204.