Annexin A3

Annexin A3
PDB rendering based on 1aii.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1aii​, 1axn​
Identifiers
Symbols	ANXA3 ; ANX3
External IDs	Template:OMIM5 Template:MGI HomoloGene: 68445
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Annexin A3, also known as ANXA3, is a human gene.

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Further reading

• Tait JF, Frankenberry DA, Miao CH; et al. (1991). "Chromosomal localization of the human annexin III (ANX3) gene". Genomics. 10 (2): 441–8. PMID 1830024.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ernst JD, Hoye E, Blackwood RA, Jaye D (1990). "Purification and characterization of an abundant cytosolic protein from human neutrophils that promotes Ca2(+)-dependent aggregation of isolated specific granules". J. Clin. Invest. 85 (4): 1065–71. PMID 2138632.CS1 maint: Multiple names: authors list (link)
• Ross TS, Tait JF, Majerus PW (1990). "Identity of inositol 1,2-cyclic phosphate 2-phosphohydrolase with lipocortin III". Science. 248 (4955): 605–7. PMID 2159184.CS1 maint: Multiple names: authors list (link)
• Pepinsky RB, Tizard R, Mattaliano RJ; et al. (1988). "Five distinct calcium and phospholipid binding proteins share homology with lipocortin I.". J. Biol. Chem. 263 (22): 10799–811. PMID 2968983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tait JF, Sakata M, McMullen BA; et al. (1989). "Placental anticoagulant proteins: isolation and comparative characterization four members of the lipocortin family". Biochemistry. 27 (17): 6268–76. PMID 2975506.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tait JF, Smith C, Xu L, Cookson BT (1994). "Structure and polymorphisms of the human annexin III (ANX3) gene". Genomics. 18 (1): 79–86. doi:10.1006/geno.1993.1428. PMID 8276419.CS1 maint: Multiple names: authors list (link)
• Sekar MC, Sambandam V, Grizzle WE, McDonald JM (1996). "Dissociation of cyclic inositol phosphohydrolase activity from annexin III". J. Biol. Chem. 271 (14): 8295–9. PMID 8626524.CS1 maint: Multiple names: authors list (link)
• Favier-Perron B, Lewit-Bentley A, Russo-Marie F (1996). "The high-resolution crystal structure of human annexin III shows subtle differences with annexin V.". Biochemistry. 35 (6): 1740–4. doi:10.1021/bi952092o. PMID 8639653.CS1 maint: Multiple names: authors list (link)
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.CS1 maint: Multiple names: authors list (link)
• Cargill M, Altshuler D, Ireland J; et al. (1999). "Characterization of single-nucleotide polymorphisms in coding regions of human genes". Nat. Genet. 22 (3): 231–8. doi:10.1038/10290. PMID 10391209.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bödeker H, Keim V, Fiedler F; et al. (2000). "PAP I interacts with itself, PAP II, PAP III, and lithostathine/regIalpha". Mol. Cell Biol. Res. Commun. 2 (3): 150–4. doi:10.1006/mcbr.1999.0166. PMID 10662590.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gevaert K, Goethals M, Martens L; et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bruneel A, Labas V, Mailloux A; et al. (2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876–84. doi:10.1002/pmic.200401239. PMID 16130169.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stelzl U, Worm U, Lalowski M; et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Park JE, Lee DH, Lee JA; et al. (2005). "Annexin A3 is a potential angiogenic mediator". Biochem. Biophys. Res. Commun. 337 (4): 1283–7. doi:10.1016/j.bbrc.2005.10.004. PMID 16236264.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)