Difference between revisions of "Angioedema"

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(Differentiating Angioedema from other Diseases)
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{{Angioedema}}
+
{{SI}}                                                                  
'''For patient information, click [[Angioedema (patient information)|here]]'''
+
{{CMG}}
 +
==Overview==
  
{{CMG}}; {{AE}} {{CZ}}
+
==Historical Perspective==
 +
*[Disease name] was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
 +
*In [year], [gene] mutations were first identified in the pathogenesis of [disease name].
 +
*In [year], the first [discovery] was developed by [scientist] to treat/diagnose [disease name].
 +
 +
==Classification==
 +
*[Disease name] may be classified according to [classification method] into [number] subtypes/groups:
 +
:*[group1]
 +
:*[group2]
 +
:*[group3]
 +
*Other variants of [disease name] include [disease subtype 1], [disease subtype 2], and [disease subtype 3].
 +
 +
==Pathophysiology==
 +
*The pathogenesis of [disease name] is characterized by [feature1], [feature2], and [feature3].
 +
*The [gene name] gene/Mutation in [gene name] has been associated with the development of [disease name], involving the [molecular pathway] pathway.
 +
*On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
 +
*On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
  
{{SK}} Quincke's edema; angiooedema; angio-edema; angioneurotic edema; welts
+
==Clinical Features== 
  
==[[Angioedema overview|Overview]]==
+
==Differentiating [disease name] from other Diseases==
 +
*[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as:
 +
:*[Differential dx1]
 +
:*[Differential dx2]
 +
:*[Differential dx3]
 +
 +
==Epidemiology and Demographics==
 +
* The prevalence of [disease name] is approximately [number or range] per 100,000 individuals worldwide.
 +
* In [year], the incidence of [disease name] was estimated to be [number or range] cases per 100,000 individuals in [location].
 +
 +
===Age===
 +
*Patients of all age groups may develop [disease name].
 +
 +
*[Disease name] is more commonly observed among patients aged [age range] years old.
 +
*[Disease name] is more commonly observed among [elderly patients/young patients/children].
 +
 +
===Gender===
 +
*[Disease name] affects men and women equally.
 +
 +
*[Gender 1] are more commonly affected with [disease name] than [gender 2].
 +
* The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.
 +
 +
===Race===
 +
*There is no racial predilection for [disease name].
 +
 +
*[Disease name] usually affects individuals of the [race 1] race.
 +
*[Race 2] individuals are less likely to develop [disease name].
 +
 +
==Risk Factors==
 +
*Common risk factors in the development of [disease name] are [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].
 +
 +
== Natural History, Complications and Prognosis==
 +
*The majority of patients with [disease name] remain asymptomatic for [duration/years].
 +
*Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
 +
*If left untreated, [#%] of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
 +
*Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
 +
*Prognosis is generally [excellent/good/poor], and the [1/5/10­year mortality/survival rate] of patients with [disease name] is approximately [#%].
  
==[[Angioedema historical perspective|Historical Perspective]]==
+
== Diagnosis ==
 +
===Diagnostic Criteria===
 +
*The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met:
 +
:*[criterion 1]
 +
:*[criterion 2]
 +
:*[criterion 3]
 +
:*[criterion 4]
 +
 +
=== Symptoms ===
 +
*[Disease name] is usually asymptomatic.
 +
*Symptoms of [disease name] may include the following:
 +
:*[symptom 1]
 +
:*[symptom 2]
 +
:*[symptom 3]
 +
:*[symptom 4]
 +
:*[symptom 5]
 +
:*[symptom 6]
 +
 +
=== Physical Examination ===
 +
*Patients with [disease name] usually appear [general appearance].
 +
*Physical examination may be remarkable for:
 +
:*[finding 1]
 +
:*[finding 2]
 +
:*[finding 3]
 +
:*[finding 4]
 +
:*[finding 5]
 +
:*[finding 6]
  
==[[Angioedema classification|Classification]]==
+
=== Laboratory Findings ===
==[[Angioedema causes|Causes]]==
+
*There are no specific laboratory findings associated with [disease name].
  
==[[Angioedema pathophysiology|Pathophysiology]]==
+
*A  [positive/negative] [test name] is diagnostic of [disease name].
==[[Differentiating angioedema from other diseases|Differentiating Angioedema from other Diseases]]==
+
*An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of [disease name].
 +
*Other laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
 +
 +
===Imaging Findings===
 +
*There are no [imaging study] findings associated with [disease name].
 +
 +
*[Imaging study 1] is the imaging modality of choice for [disease name].
 +
*On [imaging study 1], [disease name] is characterized by [finding 1], [finding 2], and [finding 3].
 +
*[Imaging study 2] may demonstrate [finding 1], [finding 2], and [finding 3].
 +
 +
=== Other Diagnostic Studies ===
 +
*[Disease name] may also be diagnosed using [diagnostic study name].
 +
*Findings on [diagnostic study name] include [finding 1], [finding 2], and [finding 3].
 +
 +
== Treatment ==
 +
=== Medical Therapy ===
 +
*There is no treatment for [disease name]; the mainstay of therapy is supportive care.
 +
 +
*The mainstay of therapy for [disease name] is [medical therapy 1] and [medical therapy 2].
 +
*[Medical therapy 1] acts by [mechanism of action 1].
 +
*Response to [medical therapy 1] can be monitored with [test/physical finding/imaging] every [frequency/duration].
 +
 +
=== Surgery ===
 +
*Surgery is the mainstay of therapy for [disease name].
 +
*[Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of [disease name].
 +
*[Surgical procedure] can only be performed for patients with [disease stage] [disease name].
 +
 +
=== Prevention ===
 +
*There are no primary preventive measures available for [disease name].
 +
 +
*Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].
  
==[[Angioedema epidemiology and demographics|Epidemiology and Demographics]]==
+
*Once diagnosed and successfully treated, patients with [disease name] are followed-up every [duration]. Follow-up testing includes [test 1], [test 2], and [test 3].
 +
==References==
 +
{{Reflist|2}}
 +
 +
[[Category:Pick One of 28 Approved]]
  
==[[Angioedema risk factors|Risk Factors]]==
+
{{WS}}
==[[Angioedema screening|Screening]]==
+
{{WH}}
 
 
==[[Angioedema natural history|Natural History, Complications and Prognosis]]==
 
 
 
==Diagnosis==
 
 
 
[[Angioedema history and symptoms|History and Symptoms ]] | [[ Angioedema physical examination|Physical Examination]] | [[Angioedema laboratory findings|Laboratory Findings]] | [[Angioedema chest x ray|Chest X Ray]] | [[ Angioedema other imaging findings|Other Imaging Findings]] | [[Angioedema other diagnostic studies|Other Diagnostic Studies]]
 
 
 
==Treatment==
 
[[Angioedema medical therapy|Medical Therapy]] | [[Angioedema primary prevention|Primary Prevention]] | [[Angioedema secondary prevention|Secondary Prevention]] | [[Angioedema cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] |  [[Angioedema future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
 
[[Angioedema case study one|Case #1]]
 
 
 
{{Immune disorders}}
 
{{Consequences of external causes}}
 
 
 
[[Category:Medical emergencies]]
 
[[Category:Autoimmune diseases]]
 
[[Category:Dermatology]]
 
[[Category:Gastroenterology]]
 
[[Category:Emergency medicine]]
 
[[Category:Allergology]]
 
[[Category:Intensive care medicine]]
 
[[Category:Pulmonology]]
 
[[Category:Signs and symptoms]]
 
[[Category:Disease]]
 
[[Category:Immunology]]
 
 
 
{{WikiDoc Help Menu}}
 
{{WikiDoc Sources}}
 

Revision as of 15:43, 1 November 2018

WikiDoc Resources for Angioedema

Articles

Most recent articles on Angioedema

Most cited articles on Angioedema

Review articles on Angioedema

Articles on Angioedema in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Angioedema

Images of Angioedema

Photos of Angioedema

Podcasts & MP3s on Angioedema

Videos on Angioedema

Evidence Based Medicine

Cochrane Collaboration on Angioedema

Bandolier on Angioedema

TRIP on Angioedema

Clinical Trials

Ongoing Trials on Angioedema at Clinical Trials.gov

Trial results on Angioedema

Clinical Trials on Angioedema at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Angioedema

NICE Guidance on Angioedema

NHS PRODIGY Guidance

FDA on Angioedema

CDC on Angioedema

Books

Books on Angioedema

News

Angioedema in the news

Be alerted to news on Angioedema

News trends on Angioedema

Commentary

Blogs on Angioedema

Definitions

Definitions of Angioedema

Patient Resources / Community

Patient resources on Angioedema

Discussion groups on Angioedema

Patient Handouts on Angioedema

Directions to Hospitals Treating Angioedema

Risk calculators and risk factors for Angioedema

Healthcare Provider Resources

Symptoms of Angioedema

Causes & Risk Factors for Angioedema

Diagnostic studies for Angioedema

Treatment of Angioedema

Continuing Medical Education (CME)

CME Programs on Angioedema

International

Angioedema en Espanol

Angioedema en Francais

Business

Angioedema in the Marketplace

Patents on Angioedema

Experimental / Informatics

List of terms related to Angioedema

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

  • [Disease name] was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
  • In [year], [gene] mutations were first identified in the pathogenesis of [disease name].
  • In [year], the first [discovery] was developed by [scientist] to treat/diagnose [disease name].

Classification

  • [Disease name] may be classified according to [classification method] into [number] subtypes/groups:
  • [group1]
  • [group2]
  • [group3]
  • Other variants of [disease name] include [disease subtype 1], [disease subtype 2], and [disease subtype 3].

Pathophysiology

  • The pathogenesis of [disease name] is characterized by [feature1], [feature2], and [feature3].
  • The [gene name] gene/Mutation in [gene name] has been associated with the development of [disease name], involving the [molecular pathway] pathway.
  • On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
  • On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

Clinical Features

Differentiating [disease name] from other Diseases

  • [Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as:
  • [Differential dx1]
  • [Differential dx2]
  • [Differential dx3]

Epidemiology and Demographics

  • The prevalence of [disease name] is approximately [number or range] per 100,000 individuals worldwide.
  • In [year], the incidence of [disease name] was estimated to be [number or range] cases per 100,000 individuals in [location].

Age

  • Patients of all age groups may develop [disease name].
  • [Disease name] is more commonly observed among patients aged [age range] years old.
  • [Disease name] is more commonly observed among [elderly patients/young patients/children].

Gender

  • [Disease name] affects men and women equally.
  • [Gender 1] are more commonly affected with [disease name] than [gender 2].
  • The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.

Race

  • There is no racial predilection for [disease name].
  • [Disease name] usually affects individuals of the [race 1] race.
  • [Race 2] individuals are less likely to develop [disease name].

Risk Factors

  • Common risk factors in the development of [disease name] are [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].

Natural History, Complications and Prognosis

  • The majority of patients with [disease name] remain asymptomatic for [duration/years].
  • Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
  • If left untreated, [#%] of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
  • Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
  • Prognosis is generally [excellent/good/poor], and the [1/5/10­year mortality/survival rate] of patients with [disease name] is approximately [#%].

Diagnosis

Diagnostic Criteria

  • The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met:
  • [criterion 1]
  • [criterion 2]
  • [criterion 3]
  • [criterion 4]

Symptoms

  • [Disease name] is usually asymptomatic.
  • Symptoms of [disease name] may include the following:
  • [symptom 1]
  • [symptom 2]
  • [symptom 3]
  • [symptom 4]
  • [symptom 5]
  • [symptom 6]

Physical Examination

  • Patients with [disease name] usually appear [general appearance].
  • Physical examination may be remarkable for:
  • [finding 1]
  • [finding 2]
  • [finding 3]
  • [finding 4]
  • [finding 5]
  • [finding 6]

Laboratory Findings

  • There are no specific laboratory findings associated with [disease name].
  • A [positive/negative] [test name] is diagnostic of [disease name].
  • An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of [disease name].
  • Other laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

Imaging Findings

  • There are no [imaging study] findings associated with [disease name].
  • [Imaging study 1] is the imaging modality of choice for [disease name].
  • On [imaging study 1], [disease name] is characterized by [finding 1], [finding 2], and [finding 3].
  • [Imaging study 2] may demonstrate [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

  • [Disease name] may also be diagnosed using [diagnostic study name].
  • Findings on [diagnostic study name] include [finding 1], [finding 2], and [finding 3].

Treatment

Medical Therapy

  • There is no treatment for [disease name]; the mainstay of therapy is supportive care.
  • The mainstay of therapy for [disease name] is [medical therapy 1] and [medical therapy 2].
  • [Medical therapy 1] acts by [mechanism of action 1].
  • Response to [medical therapy 1] can be monitored with [test/physical finding/imaging] every [frequency/duration].

Surgery

  • Surgery is the mainstay of therapy for [disease name].
  • [Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of [disease name].
  • [Surgical procedure] can only be performed for patients with [disease stage] [disease name].

Prevention

  • There are no primary preventive measures available for [disease name].
  • Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].
  • Once diagnosed and successfully treated, patients with [disease name] are followed-up every [duration]. Follow-up testing includes [test 1], [test 2], and [test 3].

References



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