Anaphylaxis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Dushka Riaz, MD
Epidemiology and Demographics
Prevalence
- In 2006, the lifetime prevalence of Anaphylaxis was estimated to be 0.05% to 2% in the United States. However it is believed that this is an underestimation because the disease is underdiagnosed. [1]
Case-fatality rate/Mortality rate
- The mortality rate of Anaphylaxis is approximately 186 to 225 deaths/year. [2]
Age
- Patients of all age groups may develop anaphylaxis, however, children and adolescents account for the majority of cases.[3]
Race
- There is no racial predilection to anaphylaxis.
Gender
- Anaphylaxis affects men and women equally with more women being admitted to the hospital for the disease. [1]
Region
- There is no regional predilection to anaphylaxis.
Developed Countries
An estimated 1.24% to 16.8% of the United States population is considered at risk for developing anaphylaxis if they are exposed to one or more allergens. [4] Anaphylaxis results in fewer than 1,000 deaths per year in the U.S. (compared to 2.4 million deaths from all causes each year in the U.S.[5]). The most common presentation includes sudden cardiovascular collapse (88% of reported cases of severe anaphylaxis).
References
- ↑ 1.0 1.1 LoVerde D, Iweala OI, Eginli A, Krishnaswamy G (2018). "Anaphylaxis". Chest. 153 (2): 528–543. doi:10.1016/j.chest.2017.07.033. PMC 6026262. PMID 28800865.
- ↑ Ma L, Danoff TM, Borish L (2014). "Case fatality and population mortality associated with anaphylaxis in the United States". J Allergy Clin Immunol. 133 (4): 1075–83. doi:10.1016/j.jaci.2013.10.029. PMC 3972293. PMID 24332862.
- ↑ Lieberman P, Camargo CA, Bohlke K, Jick H, Miller RL, Sheikh A; et al. (2006). "Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group". Ann Allergy Asthma Immunol. 97 (5): 596–602. doi:10.1016/S1081-1206(10)61086-1. PMID 17165265.
- ↑ Neugut, Alfred, Anita Ghatak and Rachel Miller. "Anaphylaxis in the United States: An Investigation Into Its Epidemiology." Arch Intern Med. 161.108 January 2001 15-21. 29 January 2007 <http://archinte.ama-assn.org/cgi/content/full/161/1/15>.
- ↑ "FASTSTATS - Deaths and Mortality". Retrieved 2013-02-13.