Analgesic nephropathy natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Natural History

Complications

Complications of analgesic nephropathy include pyelonephritis^[1] and end-stage kidney disease. Risk factors for poor prognosis include recurrent urinary tract infection and persistently elevated blood pressure. Analgesic nephropathy also appears to increase the risk of developing cancers of the urinary system.^[2]

Complications associated with analgesic nephropathy include:

Urinary tract infections
Varying degrees of renal failure
End stage renal disease (ESRD)
Transitional cell tumours of the urothelium (in abuse of analgesics containing phenacetin)

Prognosis

References

↑ Maisonneuve P, Agodoa L, Gellert R; et al. (2000). "Distribution of primary renal diseases leading to end-stage renal failure in the United States, Europe, and Australia/New Zealand: results from an international comparative study". Am. J. Kidney Dis. 35 (1): 157–65. PMID 10620560. Unknown parameter |month= ignored (help)
↑ Blohmé I, Johansson S (1981). "Renal pelvic neoplasms and atypical urothelium in patients with end-stage analgesic nephropathy". Kidney Int. 20 (5): 671–5. PMID 7045494. Unknown parameter |month= ignored (help)

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[pmid10620560-1] Maisonneuve P, Agodoa L, Gellert R; et al. (2000). "Distribution of primary renal diseases leading to end-stage renal failure in the United States, Europe, and Australia/New Zealand: results from an international comparative study". Am. J. Kidney Dis. 35 (1): 157–65. PMID 10620560. Unknown parameter |month= ignored (help)

[pmid7045494-2] Blohmé I, Johansson S (1981). "Renal pelvic neoplasms and atypical urothelium in patients with end-stage analgesic nephropathy". Kidney Int. 20 (5): 671–5. PMID 7045494. Unknown parameter |month= ignored (help)

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