Alpha-4 beta-2 nicotinic receptor

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Overview

The alpha-4 beta-2 nicotinic receptor ((α4)2(β2)3) is a type of nicotinic acetylcholine receptor, consisting of α4 and β2 subunits[1].

It is located in the brain, where activation yields post- and presynaptic excitation[1], mainly by increased Na+ and K+ permeability.

Agonists

Nicotinic agonists for this receptor include:

Antagonists

References

  1. ↑ 1.0 1.1 Pharmacology, (Rang, Dale, Ritter & Moore, ISBN 0443071454, 5:th ed., Churchill Livingstone 2003) Page 138.


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