Alopecia other diagnostic studies: Difference between revisions

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{{Alopecia}}
{{Alopecia}}
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{{CMG}} [[Ogechukwu Hannah Nnabude, MD]]
 
==Overview==
 
There are tests that can be completed outside of the laboratory that will help to confirm the diagnosis.
 
==Other Diagnostic Studies==
==Other Diagnostic Studies==


There are tests that can be completed outside of the laboratory that will help to confirm the diagnosis.
'''Hair Pull Test'''
 
Test for excessive shedding, it is not diagnostic of a particular hair loss but indicates active hair loss is occurring. Hair should not be washed 24-48 hour prior to a hair pull test. It is performed by gently grasping 40-60 hairs and gently pull upward from different parts of the scalp.
A positive test is when three to six or more strands are pulled out.
The pull test is positive in:
* androgenetic alopecia
* alopecia areata and scarring alopecia
* telogen effluvium
* anagen effluvium
* loose anagen syndrome
Evaluation of the pulled hair may uncover vital information. For example, if the bulb of the hair is dark, it indicates that the hair is in the anagen phase or if it is white, it indicates that the hair is in the telogen phase.
 
'''Trichoscopy'''
 
This is a noninvasive method of examining hair and scalp. The test may be performed with the use of a dermoscope or a video dermoscope. <ref name="pmid18664157">{{cite journal| author=Rudnicka L, Olszewska M, Rakowska A, Kowalska-Oledzka E, Slowinska M| title=Trichoscopy: a new method for diagnosing hair loss. | journal=J Drugs Dermatol | year= 2008 | volume= 7 | issue= 7 | pages= 651-4 | pmid=18664157 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18664157  }} </ref> The Alopecia Areata Predictive Score makes use of it to predict the treatment outcome in patients with patchy alopecia areata. <ref name="pmid31301100">Waśkiel-Burnat A, Rakowska A, Sikora M, Olszewska M, Rudnicka L (2020) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=31301100 Alopecia areata predictive score: A new trichoscopy-based tool to predict treatment outcome in patients with patchy alopecia areata.] ''J Cosmet Dermatol'' 19 (3):746-751. [http://dx.doi.org/10.1111/jocd.13064 DOI:10.1111/jocd.13064] PMID: [https://pubmed.gov/31301100 31301100]</ref>
 
'''Biopsy'''
 
A biopsy will reveal the most information regarding hair loss.


*Pull test: Firm pull on 20-40 hairs should yield fallout of no more than 1 in 10 hairs
'''Microbiology Testing'''
**Increased # telogen hairs with depigmented proximal bulb:  [[Telogen effluvium]]
Potasium hydroxide preparation and fungal culture can be used in the diagnosis of tinea capitis. Woods light can also be used to check for signs of fungal infection.
**Increased # hairs with no bulb:  Breakage (hair fragility due to exogenous injury)
**[[Anagen hair]]s with pigmented root: Likely excessive force
*Follicular units:  Number of hairs produced per follicular orifice
**Threes = normal for ages 20-40
**Twos = normal for ages 40-60
**Ones = normal for ages > 60
**Voids = follicular orifices without hairs suggests advanced [[androgenetic alopecia]] if no scarring


==References==
==References==

Revision as of 03:11, 12 December 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ogechukwu Hannah Nnabude, MD

Overview

There are tests that can be completed outside of the laboratory that will help to confirm the diagnosis.

Other Diagnostic Studies

Hair Pull Test

Test for excessive shedding, it is not diagnostic of a particular hair loss but indicates active hair loss is occurring. Hair should not be washed 24-48 hour prior to a hair pull test. It is performed by gently grasping 40-60 hairs and gently pull upward from different parts of the scalp. A positive test is when three to six or more strands are pulled out. The pull test is positive in:

  • androgenetic alopecia
  • alopecia areata and scarring alopecia
  • telogen effluvium
  • anagen effluvium
  • loose anagen syndrome

Evaluation of the pulled hair may uncover vital information. For example, if the bulb of the hair is dark, it indicates that the hair is in the anagen phase or if it is white, it indicates that the hair is in the telogen phase.

Trichoscopy

This is a noninvasive method of examining hair and scalp. The test may be performed with the use of a dermoscope or a video dermoscope. [1] The Alopecia Areata Predictive Score makes use of it to predict the treatment outcome in patients with patchy alopecia areata. [2]

Biopsy

A biopsy will reveal the most information regarding hair loss.

Microbiology Testing Potasium hydroxide preparation and fungal culture can be used in the diagnosis of tinea capitis. Woods light can also be used to check for signs of fungal infection.

References

  1. Rudnicka L, Olszewska M, Rakowska A, Kowalska-Oledzka E, Slowinska M (2008). "Trichoscopy: a new method for diagnosing hair loss". J Drugs Dermatol. 7 (7): 651–4. PMID 18664157.
  2. Waśkiel-Burnat A, Rakowska A, Sikora M, Olszewska M, Rudnicka L (2020) Alopecia areata predictive score: A new trichoscopy-based tool to predict treatment outcome in patients with patchy alopecia areata. J Cosmet Dermatol 19 (3):746-751. DOI:10.1111/jocd.13064 PMID: 31301100

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