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==Overview==
==Overview==
[[Alopecia]] can be subdivided into two main categories: non-scarring and scarring. Over all, non-scarring alopecia has a higher possibility of being reversible and having a better outcome while scarring alopecia is more likely to be irreversible and have a poorer outcome.
[[Alopecia]] can be subdivided into two main categories: non-scarring and scarring. Over all, [[non-scarring alopecia]] has a higher possibility of being reversible and having a better outcome while [[scarring alopecia]] is more likely to be irreversible and have a poorer outcome.


==Classification==
==Classification==
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'''The six major categories of non-scarring alopecia are''':  
'''The six major categories of non-scarring alopecia are''':  


* '''[[Alopecia areata]]''': this can affect any part of the body. When it affects only a portion of an area of the body, it is called [[alopecia areata]]. When it affects the entire site, it is called [[alopecia totalis]]. When it involves the whole body, it is called [[alopecia Universalis]]. The etiology is unknown, but it might be related to an autoimmune disease.<ref name="pmid30502419">{{cite journal| author=Lee YB, Jun M, Lee WS| title=Alopecia areata and poliosis: A retrospective analysis of 258 cases. | journal=J Am Acad Dermatol | year= 2019 | volume= 80 | issue= 6 | pages= 1776-1778 | pmid=30502419 | doi=10.1016/j.jaad.2018.11.033 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30502419  }} </ref>  
* '''[[Alopecia areata]]''': this can affect any part of the body. When it affects only a portion of an area of the body, it is called [[alopecia areata]]. When it affects the entire site, it is called [[alopecia totalis]]. When it involves the whole body, it is called [[alopecia Universalis]]. The etiology is unknown, but it might be related to an [[autoimmune disease]].<ref name="pmid30502419">{{cite journal| author=Lee YB, Jun M, Lee WS| title=Alopecia areata and poliosis: A retrospective analysis of 258 cases. | journal=J Am Acad Dermatol | year= 2019 | volume= 80 | issue= 6 | pages= 1776-1778 | pmid=30502419 | doi=10.1016/j.jaad.2018.11.033 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30502419  }} </ref>  


* '''[[Anagen effluvium]]''': This is hair shedding that occurs during the [[anagen phase]] of the cell cycle. Seen in cancer patients who are receiving [[chemotherapeutic agents]].
* '''[[Anagen effluvium]]''': This is hair shedding that occurs during the [[anagen phase]] of the cell cycle. Seen in cancer patients who are receiving [[chemotherapeutic agents]].
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* [['''Tinea capitis''']]: the classical kind of [[tinea capitis]] (black-dots) causes non-scarring hair loss, unlike other types like [[kerion]] and [[favus]].
* [['''Tinea capitis''']]: the classical kind of [[tinea capitis]] (black-dots) causes non-scarring hair loss, unlike other types like [[kerion]] and [[favus]].


* '''[[Traumatic alopecia]]''': This results from forceful traction of the hair. It is commonly seen in children and is similar to [[traction alopecia]]. Also, trichotillomania is a type of traumatic alopecia in which the patient pulls on his/her hair repeatedly. <ref name="pmid30501438">{{cite journal| author=Chen P, Chen F, Zhou B| title=The risk of dermatological toxicities of combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma patients: a systematic review and meta-analysis. | journal=Cutan Ocul Toxicol | year= 2019 | volume= 38 | issue= 2 | pages= 105-111 | pmid=30501438 | doi=10.1080/15569527.2018.1553180 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30501438  }} </ref>
* '''[[Traumatic alopecia]]''': This results from forceful traction of the hair. It is commonly seen in children and is similar to [[traction alopecia]]. Also, [[trichotillomania]] is a type of traumatic [[alopecia]] in which the patient pulls on his/her hair repeatedly. <ref name="pmid30501438">{{cite journal| author=Chen P, Chen F, Zhou B| title=The risk of dermatological toxicities of combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma patients: a systematic review and meta-analysis. | journal=Cutan Ocul Toxicol | year= 2019 | volume= 38 | issue= 2 | pages= 105-111 | pmid=30501438 | doi=10.1080/15569527.2018.1553180 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30501438  }} </ref>


'''Scarring alopecia is divided into three major types''':
'''Scarring alopecia is divided into three major types''':

Revision as of 05:39, 20 February 2021


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogechukwu Hannah Nnabude, MD

Overview

Alopecia can be subdivided into two main categories: non-scarring and scarring. Over all, non-scarring alopecia has a higher possibility of being reversible and having a better outcome while scarring alopecia is more likely to be irreversible and have a poorer outcome.

Classification

Alopecia may be classified according to the scarring into 2 subtypes/groups: non-scarring and scarring.
The six major categories of non-scarring alopecia are:

Scarring alopecia is divided into three major types:

  • Alopecia mucinosa: This occurs when mucinous material accumulates in the hair follicles and the sebaceous glands. The mucinous material causes an inflammatory response that hinders the growth of hair.

References

  1. Lee YB, Jun M, Lee WS (2019). "Alopecia areata and poliosis: A retrospective analysis of 258 cases". J Am Acad Dermatol. 80 (6): 1776–1778. doi:10.1016/j.jaad.2018.11.033. PMID 30502419.
  2. 2.0 2.1 Nalluri R, Harries M (2016) Alopecia in general medicine. Clin Med (Lond) 16 (1):74-8. DOI:10.7861/clinmedicine.16-1-74 PMID: 26833522
  3. Liu LY, King BA (2019) Response to tofacitinib therapy of eyebrows and eyelashes in alopecia areata. J Am Acad Dermatol 80 (6):1778-1779. DOI:10.1016/j.jaad.2018.11.037 PMID: 30502414
  4. Chen P, Chen F, Zhou B (2019). "The risk of dermatological toxicities of combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma patients: a systematic review and meta-analysis". Cutan Ocul Toxicol. 38 (2): 105–111. doi:10.1080/15569527.2018.1553180. PMID 30501438.
  5. 5.0 5.1 Vary JC (2015) Selected Disorders of Skin Appendages--Acne, Alopecia, Hyperhidrosis. Med Clin North Am 99 (6):1195-211. DOI:10.1016/j.mcna.2015.07.003 PMID: 26476248