Allopurinol (oral): Difference between revisions

Revision as of 23:06, 22 January 2011

Synonyms / Brand Names: Allopurinolum, Allopurinol Sodium, Alopurinol, 7HP, Adenock, Ailural, Allo-Puren, Allopur, Allozym, Allural, Aloprim, Aloral, Alositol, Aluline, Anoprolin, Anzief, Apo-Allopurinol, Apulonga, Apurin, Apurol, Atisuril, Bleminol, Bloxanth, Caplenal, Cellidrin, Cosuric, Dabrosin, Dabroson, Dura Al, Embarin, Epidropal, Epuric, Foligan, Geapur, Gichtex, Gotax, HPP, Hamarin, Hexanuret, Ketanrift, Ketobun-A, Ledopur, Lopurin, Lysuron, Milurit, Miniplanor, Monarch, Nektrohan, Progout, Purinol, Remid, Riball, Sigapurol, Suspendol, Takanarumin, Urbol, Uricemil, Uriprim, Uripurinol, Uritas, Urobenyl, Urolit, Urosin, Urtias, Urtias 100, Xanturat, Zyloprim, Zyloric, Allohexal

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

The dosage of Allopurinol to accomplish full control of gout and to lower serum uric acid to normal or near-normal levels varies with the severity of the disease. The average is 200 to 300 mg per day for patients with mild gout and 400 to 600 mg per day for those with moderately severe tophaceous gout. The appropriate dosage may be administered in divided doses or as a single equivalent dose with the 300 mg tablet. Dosage requirements in excess of 300 mg should be administered in divided doses. The minimal effective dosage is 100 to 200 mg daily and the maximal recommended dosage is 800 mg daily. To reduce the possibility of flare-up of acute gouty attacks, it is recommended that the patient start with a low dose of Allopurinol (100 mg daily) and increase at weekly intervals by 100 mg until a serum uric acid level of 6 mg/dL or less is attained but without exceeding the maximal recommended dosage.

FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.

Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.

Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.

Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information

Trial Resources
Ongoing Trials, Trial Results

Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.

Media Resources
Slides, Video, Images, MP3, Podcasts, etc.

Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.

International Resources
en Español

FDA Package Insert Resources

Indications

Contraindications

Side Effects

Drug Interactions

Precautions

Overdose

Instructions for Administration

How Supplied

Pharmacokinetics and Molecular Data

FDA on Allopurinol (oral)

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Publication Resources

Most Recent Articles on Allopurinol (oral)

Review Articles on Allopurinol (oral)

Articles on Allopurinol (oral) in N Eng J Med, Lancet, BMJ

WikiDoc State of the Art Review

Textbook Information on Allopurinol (oral)

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Trial Resources

Ongoing Trials with Allopurinol (oral) at Clinical Trials.gov

Trial Results with Allopurinol (oral)

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Guidelines & Evidence Based Medicine Resources

US National Guidelines Clearinghouse on Allopurinol (oral)

Cochrane Collaboration on Allopurinol (oral)

Cost Effectiveness of Allopurinol (oral)

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Media Resources

Powerpoint Slides on Allopurinol (oral)

Images of Allopurinol (oral)

Podcasts & MP3s on Allopurinol (oral)

Videos on Allopurinol (oral)

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Patient Resources

Patient Information from National Library of Medicine

Patient Resources on Allopurinol (oral)

Discussion Groups on Allopurinol (oral)

Patient Handouts on Allopurinol (oral)

Blogs on Allopurinol (oral)

Allopurinol (oral) in the News

Allopurinol (oral) in the Marketplace

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International Resources

Allopurinol (oral) en Español

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